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Archive: 12/09/2012

Engineered immune cells produce complete response in child with an aggressive pediatric leukemia

By reprogramming a 7-year-old girl's own immune cells to attack an aggressive form of childhood leukemia, a pediatric oncologist has achieved a complete response in his patient, who faced grim prospects when she relapsed ...

Cancer created Dec 09, 2012 | popularity 5 / 5 (1) | comments 0

Temple scientists target DNA repair to eradicate leukemia stem cells

Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant ...

Cancer created Dec 09, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Bugs without borders: Researchers track the emergence and global spread of healthcare associated Clostridium difficile

Researchers show that the global epidemic of Clostridium difficile 027/NAP1/BI in the early to mid-2000s was caused by the spread of two different but highly related strains of the bacterium rather than one as was previo ...

Genetics created Dec 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Brain study shows why some people are more in tune with what they want

Wellcome Trust researchers have discovered how the brain assesses confidence in its decisions. The findings explain why some people have better insight into their choices than others.

Neuroscience created Dec 09, 2012 | popularity 3.4 / 5 (8) | comments 0 | with audio podcast

Secrets of gentle touch revealed

Stroke the soft body of a newborn fruit fly larva ever-so-gently with a freshly plucked eyelash, and it will respond to the tickle by altering its movement—an observation that has helped scientists at the University of ...

Neuroscience created Dec 09, 2012 | popularity 5 / 5 (2) | comments 3 | with audio podcast

Steroid hormone receptor prefers working alone to shut off immune system genes

Researchers at Emory University School of Medicine have obtained a detailed molecular picture that shows how glucocorticoid hormones shut off key immune system genes.

Medical research created Dec 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Thousands protest Spain's health care austerity

(AP)—Thousands of Spanish medical workers and residents angered by budget cuts and plans to partly privatize the cherished national health service marched through some of Madrid's most famous squares on ...

Health created Dec 09, 2012 | popularity not rated yet | comments 0

Combination therapy using JAK2 and HSP90 inhibitors increased efficacy in myelofibrosis in vivo

Researchers have demonstrated that combination therapy with PU-H71 and ruxolitinib increases the durability and effectiveness of a treatment that had previously shown limited utility for patients with myelofibrosis.

Cancer created Dec 09, 2012 | popularity not rated yet | comments 0

Novel therapeutic agents provide hope for patients with hard-to-treat blood disorders

Encouraging safety and efficacy data on novel and emerging therapies presented at the 54th Annual Meeting of the American Society of Hematology (ASH) signal an important step forward in the development of treatment strategies ...

Cancer created Dec 09, 2012 | popularity not rated yet | comments 0

Targeting histone deacetylases as a new strategy for graft versus host disease prevention

New research shows that the addition of the oral anti-cancer agent vorinostat to standard therapy given before, during, and after hematopoietic stem cell transplantation (HSCT) may safely reduce the incidence and severity ...

Medical research created Dec 09, 2012 | popularity not rated yet | comments 0

New stem cell research, transplant strategies show promise to improve outcomes, reduce complications

Studies of stem cell biology and transplant approaches presented today at the 54th Annual Meeting of the American Society of Hematology (ASH) illustrate how the use of advanced modeling techniques is optimizing stem cells ...

Medical research created Dec 09, 2012 | popularity not rated yet | comments 0

More than a third of high-risk leukemia patients respond to an experimental new drug

A new drug for patients with acute myeloid leukemia (AML) marked by a specific type of genetic mutation has shown surprising promise in a Phase II clinical trial. In more than a third of participants, the leukemia was completely ...

Medications created Dec 09, 2012 | popularity not rated yet | comments 0

New drug cuts risk of deadly transplant side effect in half

A new class of drugs reduced the risk of patients contracting a serious and often deadly side effect of lifesaving bone marrow transplant treatments, according to a study from researchers at the University of Michigan Comprehensive ...

Medical research created Dec 09, 2012 | popularity not rated yet | comments 0

Rocky road ahead for implementation of Obamacare

President Barack Obama may have defeated opponents of his landmark health care law in the courts and at the ballot box, but the sweeping reforms still face a rocky road ahead.

Health created Dec 09, 2012 | popularity not rated yet | comments 0

US panel opposes pure hydrocodone painkiller

(AP)—U.S. government health experts overwhelmingly voted against a stronger version of hydrocodone on Friday, questioning the need for a new form of one of most widely abused prescription painkillers.

Medications created Dec 09, 2012 | popularity 5 / 5 (1) | comments 0