Genetics

First evidence for genetic cause for Barrett's oesophagus found

Genetic variations that are linked with the onset of Barrett's oesophagus (BE), a pre-cancerous condition of the lower end of the gullet, have been identified for the first time. The discovery of variations in regions on ...

Medications

Use of acid reflux drugs linked to higher risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology ...

Gastroenterology

Barrett's esophagus modeled in a human organ chip

Acid reflux, the backwash of stomach acid into the swallowing tube, or esophagus, is something that many experience occasionally. When it happens repeatedly and becomes a chronic problem, it can result in "Barrett's esophagus" ...

Diseases, Conditions, Syndromes

Acid reflux affects nearly a third of US adults weekly

Gastroesophageal reflux disease (GERD), a digestive disorder that causes heartburn and other uncomfortable symptoms, may affect nearly a third of U.S. adults each week, and most of those who take certain popular medications ...

Diseases, Conditions, Syndromes

Got chronic heartburn? Easy does it during the Thanksgiving feast

(HealthDay)—The turkey, stuffing, cranberries, green bean casserole and mashed potatoes on the Thanksgiving table may look tempting, but if you have gastroesophageal reflux disease (GERD) you should proceed with caution, ...

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Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is a chronic symptom of mucosal damage caused by stomach acid coming up from the stomach into the esophagus. A typical symptom is heartburn.

GERD is usually caused by changes in the barrier between the stomach and the esophagus, including abnormal relaxation of the lower esophageal sphincter, which normally holds the top of the stomach closed; impaired expulsion of gastric reflux from the esophagus, or a hiatal hernia. These changes may be permanent or temporary ("transient").

Another kind of acid reflux, which causes respiratory and laryngeal signs and symptoms, is called laryngopharyngeal reflux (LPR) or "extraesophageal reflux disease" (EERD). Unlike GERD, LPR is unlikely to produce heartburn, and is sometimes called silent reflux.

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