Acute Liver Failure

FDA advises against using extra-strength acetaminophen

Apparently, the FDA's warning four months ago was missed by many physicians, pharmacists and patients, so the drug agency, in an unusual move, saw fit Monday to remind us: Stop writing prescriptions for, stop dispensing prescriptions ...

Apr 29, 2014
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Liver damage review finds common trends

A comprehensive review of hepatotoxicity – liver damage – caused by alcohol, illicit drugs and complementary and alternative medicines has given an insight into epidemiology, risk factors, clinical manifestations, ...

Feb 18, 2014
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Estrogen fuels autoimmune liver damage

A life-threatening condition that often requires transplantation and accounts for half of all acute liver failures, autoimmune hepatitis is often precipitated by certain anesthetics and antibiotics. Researchers say these ...

Apr 30, 2013
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Acute liver failure is the appearance of severe complications rapidly after the first signs of liver disease (such as jaundice), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum albumin and the prothrombin time in the blood). The 1993 classification defines hyperacute as within 1 week, acute as 8–28 days and subacute as 4–12 weeks. It reflects the fact that the pace of disease evolution strongly influences prognosis. Underlying etiology is the other significant determinant of outcome.

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