Acute Liver Failure

Math can save Tylenol overdose patients

University of Utah mathematicians developed a set of calculus equations to make it easier for doctors to save Tylenol overdose patients by quickly estimating how much painkiller they took, when they consumed ...

Medical research created Feb 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers find novel way to prevent drug-induced liver injury

Massachusetts General Hospital (MGH) investigators have developed a novel strategy to protect the liver from drug-induced injury and improve associated drug safety. In their report receiving advance online publication in ...

Medical research created Jan 15, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists identify key protein linked to acute liver failure

New research from the Keck School of Medicine of the University of Southern California (USC) may help prevent damage to the liver caused by drugs like acetaminophen and other stressors.

Medical research created Sep 07, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Public confused about ingredients in pain relievers

People take billions of doses of over-the-counter pain relievers like Tylenol every year, but many do not pay attention to the active ingredients they contain, such as acetaminophen, according to a new Northwestern Medicine ...

Medications created May 03, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Estrogen fuels autoimmune liver damage

A life-threatening condition that often requires transplantation and accounts for half of all acute liver failures, autoimmune hepatitis is often precipitated by certain anesthetics and antibiotics. Researchers say these ...

Medical research created Apr 30, 2013 | popularity 5 / 5 (2) | comments 0

Swine cells could power artificial liver

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows.

Medical research created Feb 27, 2013 | popularity 5 / 5 (1) | comments 0

Acetaminophen overdoses in children can be life-threatening but are avoidable

Acetaminophen, a widely available over-the-counter medication, can cause liver toxicity in children if doses are exceeded, and more public education is needed to warn of potential adverse effects, states an article published ...

Medications created Jun 04, 2012 | popularity not rated yet | comments 0

Misuse of over-the-counter pain medication is potential health threat

A significant number of adults are at risk of unintentionally overdosing on over-the-counter (OTC) pain medication, according to a new study in the US by Dr. Michael Wolf, from Northwestern University in Chicago, and his ...

Medications created May 30, 2012 | popularity not rated yet | comments 0

Model predicts death due to acetaminophen overdose

(HealthDay) -- Model for Acetaminophen-induced Liver Damage (MALD), a mathematical model that utilizes commonly obtained laboratory values, including overdose amount and time elapsed since overdose, is effective ...

Medications created Feb 24, 2012 | popularity not rated yet | comments 0

Pioneering liver treatment cures British baby

British doctors on Tuesday said they had cured a baby boy of a life-threatening liver disease using a pioneering treatment in which cells are injected into the abdomen.

Diseases, Conditions, Syndromes created Nov 15, 2011 | popularity not rated yet | comments 1

Blue-green algae a danger for people, pets

(Medical Xpress) -- Warning signs have been showing up all summer: Several lakes and ponds in Kansas have been reporting contamination from toxic blue-green algae.

Health created Sep 02, 2011 | popularity 4 / 5 (2) | comments 0

Dendritic cells in liver protect against acetaminophen toxicity

NYU School of Medicine researchers have discovered that dendritic cells in the liver have a protective role against the toxicity of acetaminophen, the widely used over-the-counter pain reliever and fever reducer for adults ...

Medical research created Sep 01, 2011 | popularity not rated yet | comments 0

Red flags on pain reliever safety

For many people, pain relievers are wonder drugs, allowing them to carry on with their lives despite disabling arthritis, for instance, or recurrent headaches. But all pain relievers, whether sold over-the counter (OTC) or ...

Medications created Jul 19, 2011 | popularity 3 / 5 (2) | comments 1

Study links acetaminophen to lower prostate cancer risk

A new study from American Cancer Society researchers finds use of 30 tablets a month or more of acetaminophen for five or more years was associated with an estimated 38% lower risk of prostate cancer. The study appears in ...

Cancer created May 23, 2011 | popularity not rated yet | comments 0

Liver disease: Understanding it will enable the provision of better treatment

In this prospective study, led by Dr Richard Moreau, INSERM Research Director (Mixed Research Unit 773 "Centre de Recherche biomédicale Bichat-Beaujon"; INSERM/Université Paris Diderot) who is also a practitioner attached ...

Diseases, Conditions, Syndromes created Apr 18, 2013 | popularity not rated yet | comments 0


Acute liver failure is the appearance of severe complications rapidly after the first signs of liver disease (such as jaundice), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum albumin and the prothrombin time in the blood). The 1993 classification defines hyperacute as within 1 week, acute as 8–28 days and subacute as 4–12 weeks. It reflects the fact that the pace of disease evolution strongly influences prognosis. Underlying etiology is the other significant determinant of outcome.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Latest Spotlight News

Controlling mood through the motions of mitochondria

(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...

Scientists discover molecule triggers sensation of itch

Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as ...

Multiple research teams unable to confirm high-profile Alzheimer's study

Teams of highly respected Alzheimer's researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science.

Researchers find common childhood asthma unconnected to allergens or inflammation

Little is known about why asthma develops, how it constricts the airway or why response to treatments varies between patients. Now, a team of researchers at Weill Cornell Medical College, Columbia University Medical Center ...

Motion quotient: IQ predicted by ability to filter motion (w/ video)

A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...

Diabetes' genetic underpinnings can vary based on ethnic background, studies say

Ethnic background plays a surprisingly large role in how diabetes develops on a cellular level, according to two new studies led by researchers at the Stanford University School of Medicine.

When oxygen is short, EGFR prevents maturation of cancer-fighting miRNAs

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs (miRNAs) before it's dissolved, researchers ...

Study reveals new mechanism for estrogen suppression of liver lipid synthesis

By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.

Scientists discover cinnamon compounds' potential ability to prevent Alzheimer's

Cinnamon: Can the red-brown spice with the unmistakable fragrance and variety of uses offer an important benefit? The common baking spice might hold the key to delaying the onset of –– or warding off ...

Ferrets, pigs susceptible to H7N9 avian influenza virus

Chinese and U.S. scientists have used virus isolated from a person who died from H7N9 avian influenza infection to determine whether the virus could infect and be transmitted between ferrets. Ferrets are often used as a mammalian ...