Acute Liver Failure

Math can save Tylenol overdose patients

University of Utah mathematicians developed a set of calculus equations to make it easier for doctors to save Tylenol overdose patients by quickly estimating how much painkiller they took, when they consumed ...

Feb 27, 2012
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Public confused about ingredients in pain relievers

People take billions of doses of over-the-counter pain relievers like Tylenol every year, but many do not pay attention to the active ingredients they contain, such as acetaminophen, according to a new Northwestern Medicine ...

May 03, 2011
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Liver damage review finds common trends

A comprehensive review of hepatotoxicity – liver damage – caused by alcohol, illicit drugs and complementary and alternative medicines has given an insight into epidemiology, risk factors, clinical manifestations, ...

Feb 18, 2014
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Estrogen fuels autoimmune liver damage

A life-threatening condition that often requires transplantation and accounts for half of all acute liver failures, autoimmune hepatitis is often precipitated by certain anesthetics and antibiotics. Researchers say these ...

Apr 30, 2013
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Acute liver failure is the appearance of severe complications rapidly after the first signs of liver disease (such as jaundice), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum albumin and the prothrombin time in the blood). The 1993 classification defines hyperacute as within 1 week, acute as 8–28 days and subacute as 4–12 weeks. It reflects the fact that the pace of disease evolution strongly influences prognosis. Underlying etiology is the other significant determinant of outcome.

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