Oncology & Cancer

Making cancer stem cells visible to the immune system

Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. This protective mechanism can be tricked with drugs. In the journal Nature, scientists from Basel, Tübingen ...

Oncology & Cancer

Researchers discover an Achilles heel in a lethal leukemia

Researchers have discovered how a linkage between two proteins in acute myeloid leukemia enables cancer cells to resist chemotherapy and showed that disrupting the linkage could render the cells vulnerable to treatment. St. ...

Oncology & Cancer

Clinical importance of leukemia stem cells validated

Cancer scientists have long debated whether all cells within a tumour are equal or whether some cancer cells are more potent - a question that has been highly investigated in experimental models in the last decade. Research ...

Medical research

Could leukemia be stopped before it starts?

Acute myeloid leukemia (AML), a blood cancer affecting both adults and children, requires more than one genetic "hit" to develop. As we age, many of us acquire a mutation that enables certain of our blood cells to multiply ...

Oncology & Cancer

Novel drug shows promise against acute myeloid leukemia

In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide (small protein) drug shows promise against the often-lethal cancer acute ...

Oncology & Cancer

Genetic study of familial leukemia solves 30-year medical mystery

A decades-old medical mystery has been solved by researchers at UC San Francisco and St. Jude Children's Research Hospital in Tennessee, who have discovered a pair of inherited genetic mutations underlying a familial blood ...

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