Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models.
Mar 20, 2017
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Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the ...
Mar 1, 2017
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Cancer is a heterogeneous disease, with myriad distinct subtypes that differ in their genetic roots. As a result, cancers rely on varied pathways for survival—and respond differently to anticancer agents. The challenge ...
Feb 2, 2017
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Cincinnati Children's researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS) - a group of pre-malignant ...
Dec 29, 2016
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A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia (AML), a potentially lethal blood cancer, in a clinical trial led by investigators at Beth Israel Deaconess Medical ...
Dec 7, 2016
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Leukemia researchers at Princess Margaret Cancer Centre have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard ...
Dec 7, 2016
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Tobacco use remains the most preventable cause of cancer, and 40 percent of diagnosed US cancer cases may have a link to its use, health authorities said Thursday.
Nov 10, 2016
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An international team of researchers from the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (PCGP) has completed a detailed map of the genomic landscape for core-binding factor ...
Oct 31, 2016
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Researchers at the Medical University of South Carolina Hollings Cancer Center have discovered a mechanism that confers resistance to drugs used to treat certain types of acute myeloid leukemia (AML). Targeting this pathway ...
Oct 21, 2016
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FLT3 inhibitors are a promising new class of drugs targeting acute myeloid leukemia (AML). However, these inhibitors alone tend not to result in long-term control of the disease. A University of Colorado Cancer Center study ...
Oct 11, 2016
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