Adenovirus

Bird flu expert working on vaccine that protects against multiple strains

(Medical Xpress)—As the bird flu outbreak in China worsens, a Purdue University expert is working on vaccines that offer broader protection against multiple strains of the virus.

Diseases, Conditions, Syndromes created May 10, 2013 | popularity not rated yet | comments 0

Viral Vectors delivery new calcium pumps for ailing hearts

(Medical Xpress)—A fresh round of trials to evaluate gene therapy for the heart is set to begin in a couple of weeks. The British Heart Foundation will be sponsoring the study, which seeks to replace defective ...

Medical research created May 01, 2013 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast report

The gene therapy renaissance: How experimental technique overcame a troubled legacy and is now helping the blind to see

(Medical Xpress)—In 1999, researchers at the University of Pennsylvania injected 19 people with a virus carrying a gene designed to correct a rare metabolic disease. Early results appeared promising: Among ...

Genetics created Apr 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Predicting the next eye pathogen; analysis of a novel adenovirus

The ongoing dance between a virus and its host distinctly shapes how the virus evolves. While human adenoviruses typically cause mild infections, recent reports have described newly characterized adenoviruses that can cause ...

Diseases, Conditions, Syndromes created Apr 10, 2013 | popularity not rated yet | comments 0

Protein may alter inevitability of osteoarthritis

Few things in life are inevitable – death, taxes, and, if you live long enough, osteoarthritis. No treatment will stop or significantly slow the disease, and joint replacement is the only definitive treatment. That may ...

Arthritis & Rheumatism created Mar 13, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Overused ophthalmology tests, treatments identified

(HealthDay)—The American Academy of Ophthalmology (AAO) is participating in the Choosing Wisely campaign and has identified five tests and treatments that may be overused.

Ophthalmology created Mar 01, 2013 | popularity not rated yet | comments 0

New cancer 'vaccine' shows future promise in treating and preventing metastatic cancers

Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center. Results from ...

Cancer created Feb 27, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Discovery in HIV may solve efficiency problems for gene therapy

A research team from Case Western Reserve University School of Medicine has discovered an approach that could make gene therapy dramatically more effective for patients.

HIV & AIDS created Feb 14, 2013 | popularity not rated yet | comments 0

Injection-free vaccination technique could address global vaccine challenge for HIV, malaria

Scientists at King's College London have demonstrated the ability to deliver a dried live vaccine to the skin without a traditional needle, and shown for the first time that this technique is powerful enough to enable specialised ...

Medical research created Feb 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists identify protective role for antibodies in Ebola vaccine study

Researchers at the National Institutes of Health (NIH) and Oregon Health & Science University (OHSU) have found that an experimental vaccine elicits antibodies that can protect nonhuman primates from Ebola virus infection.

Medical research created Jan 14, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Climate change is likely to increase the occurrence of stomach bugs, researchers predict

We can blame all sorts of things on the weather. But a stomach bug? It seems unlikely. Yet, scientists say greater quantities of rainfall and bigger storms will lead to more stomach upsets in parts of Europe. ...

Diseases, Conditions, Syndromes created Jan 07, 2013 | popularity not rated yet | comments 2

Rebuilding blood vessels through gene therapy

(Medical Xpress)—Diagnosed with severe coronary artery disease, a group of patients too ill for or not responding to other treatment options decided to take part in a clinical trial testing angiogenic gene therapy to help ...

Cardiology created Dec 21, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

First gene therapy study in human salivary gland shows promise

Gene therapy can be performed safely in the human salivary gland, according to scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

Cancer created Nov 05, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

High fever and evidence of a virus? Caution, it still may be Kawasaki disease

Clinicians should take caution when diagnosing a child who has a high fever and whose tests show evidence of adenovirus, and not assume the virus is responsible for Kawasaki-like symptoms. According to a new study from Nationwide ...

Diseases, Conditions, Syndromes created Nov 05, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Cold viruses point the way to new cancer therapies

Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ...

Cancer created Oct 16, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast


Adenoviruses are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) icosahedral viruses composed of a nucleocapsid and a double-stranded linear DNA genome. There are 57 described serotypes in humans, which are responsible for 5–10% of upper respiratory infections in children, and many infections in adults as well.

Viruses of the family Adenoviridae infect various species of vertebrates, including humans. Adenoviruses were first isolated in 1953 from human adenoids. They are classified as group I under the Baltimore classification scheme, meaning their genomes consist of double stranded DNA.

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