Adenovirus

Gene therapy for botulism

Gene therapy could be more effective than existing treatments for botulism, a rare paralytic illness caused by a nerve toxin, according to an infectious disease researcher at Cummings School.

Jul 31, 2015
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How World War II spurred vaccine innovation

War and disease have marched arm in arm for centuries. Wars magnify the spread and severity of disease by disrupting populations. As large groups of people move across borders, they introduce and encounter disease in new ...

May 08, 2015
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Adenoviruses are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) icosahedral viruses composed of a nucleocapsid and a double-stranded linear DNA genome. There are 57 described serotypes in humans, which are responsible for 5–10% of upper respiratory infections in children, and many infections in adults as well.

Viruses of the family Adenoviridae infect various species of vertebrates, including humans. Adenoviruses were first isolated in 1953 from human adenoids. They are classified as group I under the Baltimore classification scheme, meaning their genomes consist of double stranded DNA.

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