Autism results from abnormal cell communication. Testing a new theory, researchers at the University of California, San Diego School of Medicine have used a newly discovered function of an old drug to restore cell communications ...
(Medical Xpress)—Stealth is a well-known concept in military tactics. Almost since the invention of radar, the hunt began for counter-technologies to hide aircraft and missiles from detection – most successfully ...
(Medical Xpress) -- Researchers have identified a gene that controls susceptibility to drug treatment in Trypanosoma brucei, the parasite responsible for African sleeping sickness.
(Medical Xpress) -- A study published yesterday shows that a drug called fexinidazole could potentially be used to treat visceral leishmaniasis, a parasitic disease that kills 50 000 to 60 000 people ...
African-Americans with two copies of the APOL1 gene have about a 4 percent lifetime risk of developing a form of kidney disease, according to scientists at the National Institutes of Health. The finding brings scientists ...
A novel tool exploits baker's yeast to expedite the development of new drugs to fight multiple tropical diseases, including malaria, schistosomiasis, and African sleeping sickness. The unique screening method uses yeasts ...
A major new centre to boost the development of drugs to tackle the foremost diseases of the developing world is to be created at the University of Dundee.
Wild animals may be a key contributor to the continuing spread of African sleeping sickness, new research published in PLOS Computational Biology shows. The West African form of the disease, also known as Gambiense Human ...
A new oral-only treatment for sleeping sickness has entered Phase II/III clinical study in patients with late-stage sleeping sickness in the Democratic Republic of the Congo (DRC) and soon in Central African Republic (CAR). ...
(Medical Xpress) -- The savannahs and rainforests of Africa bring to mind romantic notions of wildlife, adventure and exploration. But beneath this natural beauty lies a deadly, long-neglected disease: trypanosomiasis, ...
An antiparasitic agent used to treat African sleeping sickness might someday be used to prevent nonmelanoma skin cancers. Researchers found that DFMO, or α-difluoromethylornithine, still appeared to protect against nonmelanoma ...
Across-the-board cuts to US R&D programs could have a devastating impact on efforts to develop new drugs for tuberculosis (TB) and HIV/AIDS, the world's first malaria vaccine, and other vital global health products in development, ...
The Geneva-based not-for-profit foundation FIND and Japanese diagnostics company Eiken announced today that a next-generation molecular test designed specifically for sleeping sickness a deadly parasitic disease also ...
The discovery of a potential new anti-malarial drug by a UT Southwestern Medical Center-led research team has been awarded Project of the Year by Medicines for Malaria Venture (MMV).
Jun 07, 2011
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Human African trypanosomiasis, sleeping sickness, African lethargy, or Congo trypanosomiasis is a parasitic disease of people and animals, caused by protozoa of the species Trypanosoma brucei and transmitted by the tsetse fly. The disease is endemic in some regions of sub-Saharan Africa, covering about 37 countries and 60 million people. It is estimated that 50,000 to 70,000 people are currently infected, the number having declined somewhat in recent years. The number of reported cases was below 10,000 in 2009, the first time in 50 years. It is believed that many cases go unreported. About 48,000 people died of it in 2008. Four major epidemics have occurred in recent history: one from 1896–1906 primarily in Uganda and the Congo Basin, two epidemics in 1920 and 1970 in several African countries, and a recent 2008 epidemic in Uganda.
Inside each of us is our own internal timing device. It drives everything from sleep cycles to metabolism, but the inner-workings of this so-called "circadian clock" are complex, and the molecular processes behind it have ...
Behind the common expression "you can't compare apples to oranges" lies a fundamental question of neuroscience: How does the brain recognize that apples and oranges are different? A group of neuroscientists ...
Recent research has shown that cancer cells have a much different – and more complex – metabolism than normal cells. Now, scientists at The University of Texas at Dallas have found that exploiting these differences might ...
Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point.
(Medical Xpress)—A team of combined researchers from Columbia Business School and Singapore Management University has found that people who have learned a second language become less proficient at speaking ...
Men who lose sleep during the work week may be able to lower their risk of developing Type 2 diabetes by getting more hours of sleep, according to Los Angeles Biomedical Research Institute (LA BioMed) research findings presented ...
Aspirin is known to lower risk for some cancers, and a new study led by a UC San Francisco scientist points to a possible explanation, with the discovery that aspirin slows the accumulation of DNA mutations in abnormal cells ...
(Medical Xpress)—Calories in, calories out. Any dieter is familiar with the two sides of the equation for weight loss, usually reduced to eating less and exercising more. But what controls the body's balance ...
(Medical Xpress)—When people think about genes and their relationship to cancer, most probably think about a person's hereditary cancer risk, especially after Angelina Jolie's recent news about her inherited ...