Alzheimer's disease & dementia

High metabolism is an early sign of Alzheimer's disease, finds study

An early phase in the process of developing Alzheimer's disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry. ...

Alzheimer's disease & dementia

Overactive scavenger cells may cause neurodegeneration in Alzheimer's

For the first time, researchers from the University of Zurich demonstrate a surprising effect of microglia, the scavenger cells of the brain: If these cells lack the TDP-43 protein, they not only remove Alzheimer's plaques, ...

Alzheimer's disease & dementia

Experimental Alzheimer's drug improves memory in mice

An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or SirT1, and improves memory in mice. The mice were genetically modified to have a protein ...

Cardiology

Blood vessel breakthrough major step towards Alzheimer's treatment

A breakthrough in our understanding of Alzheimer's disease has revealed changes to blood vessels in the brain, potentially presenting a path for developing new drugs to help fight the disease, according to University of Manchester ...

Alzheimer's disease & dementia

Studying the link between gum disease and Alzheimer's disease

Fusobacterium nucleatum (F. nucleatum) is a common type of bacteria that proliferates in periodontal disease. It affects the gums and jawbone, and if untreated results in unstable teeth and tooth loss. In recent years, F. ...

Neuroscience

Alzheimer's disease can be diagnosed before symptoms emerge

A large study led by Lund University in Sweden has shown that people with Alzheimer's disease can now be identified before they experience any symptoms. It is now also possible to predict who will deteriorate within the next ...

Neuroscience

Alzheimer's: Can an amino acid help to restore memories?

Scientists at the Laboratoire des Maladies Neurodégénératives (CNRS/CEA/Université Paris-Saclay) and the Neurocentre Magendie (INSERM/Université de Bordeaux) have just shown that a metabolic pathway plays a determining ...

Alzheimer's disease & dementia

Decreased deep sleep linked to early signs of Alzheimer's disease

Poor sleep is a hallmark of Alzheimer's disease. People with the disease tend to wake up tired, and their nights become even less refreshing as memory loss and other symptoms worsen. But how and why restless nights are linked ...

Neuroscience

Personality traits found to be protective in Alzheimer's disease

Alzheimer's disease, the main cause of dementia in the elderly, is a neurodegenerative disease caused by the irreversible destruction of neuronal networks in certain brain structures affecting memory. While some risk factors ...

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