Families living with four extremely rare neurodegenerative diseases have finally learned the cause of their illnesses, thanks to a researcher's hunch and decades of improvements in DNA sequencing technology.
Jul 22, 2019
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USC researchers have discovered a secret sauce in the brain's vascular system that preserves the neurons needed to keep dementia and other diseases at bay.
Jun 24, 2019
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Salk researchers have found, for the first time, that a blood-clotting protein can, unexpectedly, degrade nerves—and how nerve-supporting glial cells, including Schwann cells, provide protection. The findings, published ...
Mar 14, 2019
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A single misbehaving protein—called TDP-43—is behind 97 percent of amyotrophic lateral sclerosis (ALS) cases and 45 percent of frontotemporal dementia diagnoses. It also is found in 80 percent of chronic traumatic encephalopathy ...
Feb 27, 2019
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Scientists have discovered a new gene varitation that causes motor neurone disease (MND) in a novel biological pathway that until now hasn't been linked with neurodegeneration.
Feb 26, 2019
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Promising new research by Christian Mueller, Ph.D., and Robert H. Brown Jr., DPhil, MD, at the University of Massachusetts Medical School, provides evidence that a therapy using synthetic microRNAs may safely treat patients ...
Oct 31, 2018
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Toxic protein assemblies, or "amyloids," long considered to be key drivers in many neuromuscular diseases, also play a beneficial role in the development of healthy muscle tissue, University of Colorado Boulder researchers ...
Oct 31, 2018
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A group of Massachusetts General Hospital (MGH) investigators is proposing that targeting immune checkpoints—molecules that regulate the activity of the immune system—in immune cells called microglia could reduce the ...
Oct 17, 2018
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Few treatments exist for neurodegenerative diseases that progressively rob a person's ability to move and think, yet the results of a new study could potentially open additional approaches for exploration.
Sep 7, 2018
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A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, and some forms of frontotemporal ...
Aug 9, 2018
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