Anaphylaxis

Emergency supplies of epinephrine in schools save lives

Millions of children across the country need emergency epinephrine at school because they could suffer a severe, potentially life-threatening allergic reaction (anaphylaxis) to food or an insect sting. As schools across the ...

Nov 07, 2014
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Food allergy development linked to skin exposure

Food allergies are on the rise in the U.S. and other developed countries. In patients, food allergies appear as a variety of symptoms, ranging from mild skin inflammation to severe asthma. Recent studies suggest that contact ...

Nov 03, 2014
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FARE, ACEP develop new anaphylaxis toolkit

(HealthDay)—A new anaphylaxis toolkit has been developed to help answer questions about managing life-threatening allergies after patients are discharged from the emergency department, according to a report ...

Oct 08, 2014
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Has food allergy incidence risen in Australia?

(Medical Xpress)—In light of Food Allergy Week, Dr Robert Loblay, Sydney Medical School Immunologist and Director of the Allergy Unit at Royal Prince Alfred Hospital, has said that the incidence of food allergy has increased ...

May 13, 2014
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Taking the sting out of insect-sting allergies

(Medical Xpress)—Certain people with a history of systemic allergic reactions to insect stings are likely to benefit from immunotherapy to prevent life-threatening anaphylaxis and should, at the very least, ...

Apr 11, 2014
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Vimizim approved for rare childhood disorder

(HealthDay)—Vimizim (elosulfase alfa) has been approved by the U.S. Food and Drug Administration to treat a rare childhood disorder called Mucopolysaccharidosis Type IVA, also known as Morquio A syndrome.

Feb 17, 2014
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Anaphylaxis is defined as "a serious allergic reaction that is rapid in onset and may cause death". It typically results in a number of symptoms including an itchy rash, throat swelling, and low blood pressure. Common causes include insect bites, foods, and medications.

On a pathophysiologic level, anaphylaxis is due to the release of mediators from certain types of white blood cells triggered either by immunologic or non-immunologic mechanisms. It is diagnosed based on the presenting symptoms and signs. The primary treatment is injection of epinephrine, with other measures being complementary.

Worldwide 0.05–2% of people are estimated to have anaphylaxis at some point in their life and rates appear to be increasing. The term comes from the Greek words ἀνά ana, against, and φύλαξις phylaxis, protection.

This text uses material from Wikipedia licensed under CC BY-SA

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