Researchers help spearhead changes to global anemia guidelines
The way anemia is diagnosed worldwide could change for the first time in 50 years, following a landmark study led by WEHI researchers.
1 hour ago
0
0
The way anemia is diagnosed worldwide could change for the first time in 50 years, following a landmark study led by WEHI researchers.
1 hour ago
0
0
An international study led by researchers from Children's Hospital of Philadelphia (CHOP) has discovered an important biological cause of Fanconi anemia, a rare inherited disorder that almost universally leads to bone marrow ...
Mar 22, 2024
0
26
Children with sickle cell anemia are vulnerable to serious infections and stroke, but many do not receive the preventative care that could help them stay healthier for longer, a Children's Hospital Los Angeles study has found.
Mar 6, 2024
0
0
Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study focusing on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the ...
Feb 27, 2024
0
0
Published in the American Journal of Medical Genetics, a University of Minnesota Medical School study found that it is normal for children with Fanconi anemia to be shorter and thinner than other children. Fanconi anemia ...
Feb 26, 2024
0
0
Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get genetic analysis done at specialized private labs. The results of the DNA samples that he needed for his research weren't available for weeks and sometimes ...
Feb 6, 2024
0
44
Clinical research led by Indiana University School of Medicine investigators and their collaborators in Uganda has revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia. Their latest ...
Jan 29, 2024
0
0
As if starting life with a potentially disabling genetic blood disease wasn't enough, a study shows that almost two-thirds of babies born with sickle cell disease are born to mothers who live in disadvantaged areas.
Jan 4, 2024
0
0
Children in or adopted from the Pennsylvania foster care system with anemia may have greater odds of certain developmental and behavioral diagnoses according to a newly published study from Penn State researchers. This study, ...
Nov 16, 2023
0
43
A team at Weill Cornell Medicine has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new ...
Nov 14, 2023
0
0
Anemia (/əˈniːmiə/; also spelled anaemia and anæmia; from Greek ἀναιμία anaimia, meaning lack of blood) is a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency.
Because hemoglobin (found inside RBCs) normally carries oxygen from the lungs to the tissues, anemia leads to hypoxia (lack of oxygen) in organs. Since all human cells depend on oxygen for survival, varying degrees of anemia can have a wide range of clinical consequences.
Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis).
There are two major approaches: the "kinetic" approach which involves evaluating production, destruction and loss, and the "morphologic" approach which groups anemia by red blood cell size. The morphologic approach uses a quickly available and low cost lab test as its starting point (the MCV). On the other hand, focusing early on the question of production may allow the clinician to expose cases more rapidly where multiple causes of anemia coexist.
This text uses material from Wikipedia licensed under CC BY-SA