Autoimmune Diseases

Endogenous proteins as anti-inflammatory agents

Today the new Christian Doppler Laboratory for Complement Research was opened at the Center for Pathophysiology, Infectiology and Immunology at MedUni Vienna. The research institute, which is funded by the ...

Jun 26, 2015
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Keeping a lid on inflammation

Regulatory T cells (Treg cells) are part of the system of checks and balances that prevents the immune response from going overboard and causing autoimmune disease. Although critically important for shaping ...

Jun 17, 2015
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Transmural control of plaque formation

In atherosclerosis, fatty "plaques" form in the inner layer of arteries. As an LMU team now shows, specialized lymphoid organs found on the outer arterial wall adjacent to plaques help to restrain the inflammation ...

Jun 17, 2015
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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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