Autoimmune Diseases
Xeljanz approved for rheumatoid arthritis
(HealthDay)—Xeljanz (tofacitinib) has been approved by the U.S. Food and Drug Administration to treat symptoms of rheumatoid arthritis (RA) among people who can't tolerate, or haven't been helped by, the drug methotrexate.
Arthritis & Rheumatism
Nov 07, 2012 |
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Antirheumatic drugs have minor effect on preeclampsia risk
(HealthDay)—The use of a disease-modifying antirheumatic drug (DMARD) during pregnancy is rare and is associated with a nonsignificant increase in the risk for preeclampsia in women with autoimmune disease, ...
Diseases, Conditions, Syndromes
Nov 06, 2012 |
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Dirty pacifiers may make infants sick, study says
(HealthDay)—Pacifiers are universally popular with new parents and their infants, but there's one big problem with them: They can get dirty. Very dirty.
Pediatrics
Nov 03, 2012 |
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New MS drug proves effective where others have failed
A drug which 'reboots' a person's immune system has been shown to be an effective treatment for multiple sclerosis (MS) patients who have already failed to respond to the first drug with which they were treated (a 'first-line' ...
Neuroscience
Oct 31, 2012 |
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Women with lupus have a higher risk for preeclampsia
New research reports that women with systemic lupus erythematosus (SLE) have a two-fold increase in risk of preeclampsia—a dangerous condition in which pregnant women develop high blood pressure (hypertension) and protein ...
Diseases, Conditions, Syndromes
Oct 30, 2012 |
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A surprise mechanism uncovered in the development of lupus
In a study with a surprising outcome, scientists at Yale School of Medicine have discovered that an enzyme complex known for promoting natural resistance to bacteria and fungi unexpectedly inhibits the development ...
Diseases, Conditions, Syndromes
Oct 25, 2012 |
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Millions may be taking vitamin D unnecessarily, analysis suggests
(HealthDay)—Under the latest guidelines from the Institute of Medicine, it's possible that almost 80 million Americans who've previously been considered as having low levels of vitamin D don't need supplements ...
Health
Oct 24, 2012 |
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Research sheds light on important role of autophagy, or self-eating cells, in developing new anti-inflammatory therapies
Research just carried out in the Immunology Research Centre, led by Dr James Harris, based in the School of Biochemistry and Immunology, Trinity College Dublin, shows that the process of autophagy regulates the production ...
Medical research
Oct 24, 2012 |
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Immune cells make flexible choices
Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety of possible threats ...
Immunology
Oct 22, 2012 |
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Redefining dentistry through 'salivaomics'
(Medical Xpress)—Scientists from the UCLA School of Dentistry have been at the vanguard of research on human saliva in recent years, leading the way in the dynamic, emerging field of salivary diagnostics, ...
Dentistry
Oct 22, 2012 |
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Researchers elucidate transport pathway of immune system substances
To transport substances from the site of their production to their destination, the body needs a sophisticated transport and sorting system. Various receptors in and on the cells recognize certain molecules, pack them and ...
Immunology
Oct 18, 2012 |
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Vitamin D supplements may benefit lupus patients
A new clinical study published in BioMedCentral's open access journal Arthritis Research and Therapy provides preliminary evidence that vitamin D supplementation could be considered an immunomodulatory agent for systemic lupus ...
Arthritis & Rheumatism
Oct 16, 2012 |
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People with severe psoriasis nearly twice at risk for diabetes
An analysis of 27 studies linking psoriasis in 314,000 individuals with diabetes has found strong correlation between the scaly skin rash and the blood sugar disorder that predisposes patients to heart disease, say UC Davis ...
Diseases, Conditions, Syndromes
Oct 15, 2012 |
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Rare B cells regulate immune responses, may offer novel treatment for autoimmune diseases
Reproducing a rare type of B cell in the laboratory and infusing it back into the body may provide an effective treatment for severe autoimmune diseases such as multiple sclerosis or rheumatoid arthritis, according to researchers ...
Medical research
Oct 14, 2012 |
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Research scores advance in manipulating T-cells
(Medical Xpress)—Until recently, medical researchers had little hope of experimentally manipulating naïve T cells to study their crucial roles in immune function, because they were largely impenetrable, ...
Medical research
Oct 11, 2012 |
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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.
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Lymphatic fluid takes detour
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