Autoimmune Diseases

Finnish researchers identify the cause for LGL leukemia

Researchers of the University of Helsinki, Helsinki University Central Hospital and Institute for Molecular Medicine Finland, have discovered that a mutation in the STAT3 gene is an underlying cause for LGL leukemia. Since ...

Cancer created May 16, 2012 | popularity not rated yet | comments 0

New findings shift research direction in lupus and asthma

(Medical Xpress) -- Newfound details of the immune system suggest a role for never-before-considered drug classes in the treatment of allergic and autoimmune diseases, according to a University of Alabama at Birmingham study ...

Immunology created May 29, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Mutation drives viral sensors to initiate autoimmune disease

A new study uses a mouse model of a human autoimmune disease to reveal how abnormal regulation of the intracellular sensors that detect invading viruses can lead to autoimmune pathology. The research, published online on ...

Immunology created Jan 26, 2012 | popularity not rated yet | comments 0

Researchers elucidate transport pathway of immune system substances

To transport substances from the site of their production to their destination, the body needs a sophisticated transport and sorting system. Various receptors in and on the cells recognize certain molecules, pack them and ...

Immunology created Oct 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

Rheumatoid arthritis can be costly

(HealthDay)—Workers with rheumatoid arthritis have higher health care and other costs for U.S. employers than workers without the condition, a new study finds.

Arthritis & Rheumatism created Mar 15, 2013 | popularity not rated yet | comments 0

Millions may be taking vitamin D unnecessarily, analysis suggests

(HealthDay)—Under the latest guidelines from the Institute of Medicine, it's possible that almost 80 million Americans who've previously been considered as having low levels of vitamin D don't need supplements ...

Health created Oct 24, 2012 | popularity 5 / 5 (1) | comments 0

A genetic accelerator hits the gas on autoimmune diseases

A "genetic accelerator" is responsible for the most severe cases of Lupus (systemic lupus erythemathosus), an autoimmune disease: the accelerator, called enhancer HS1.2, speeds up the activity of some critical genes of the ...

Immunology created Jan 16, 2012 | popularity 4 / 5 (1) | comments 0

Discovery of immune cells that protect against multiple sclerosis offers hope for new treatment

In multiple sclerosis, the immune system attacks nerves in the brain and spinal cord, causing movement problems, muscle weakness and loss of vision. Immune cells called dendritic cells, which were previously thought to contribute ...

Immunology created Aug 16, 2012 | popularity not rated yet | comments 0 | with audio podcast

A surprise mechanism uncovered in the development of lupus

In a study with a surprising outcome, scientists at Yale School of Medicine have discovered that an enzyme complex known for promoting natural resistance to bacteria and fungi unexpectedly inhibits the development ...

Diseases, Conditions, Syndromes created Oct 25, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Retina's thickness may be tied to severity of MS, study suggests

(HealthDay)—Using a high-tech imaging process to measure the thickness of the eye's retina may one day predict the progression of multiple sclerosis, a new study suggests.

Neuroscience created Oct 01, 2012 | popularity not rated yet | comments 0 | with audio podcast

People with severe psoriasis nearly twice at risk for diabetes

An analysis of 27 studies linking psoriasis in 314,000 individuals with diabetes has found strong correlation between the scaly skin rash and the blood sugar disorder that predisposes patients to heart disease, say UC Davis ...

Diseases, Conditions, Syndromes created Oct 15, 2012 | popularity not rated yet | comments 0 | with audio podcast

Vitamin D supplements may protect against viral infections during the winter

Vitamin D may be known as the sunshine vitamin, but a new research report appearing in the Journal of Leukocyte Biology shows that it is more than that. According to the report, insufficient levels of vitamin D are relate ...

Health created Apr 30, 2012 | popularity 5 / 5 (1) | comments 1

Study discovers three new lupus genes

Three newly confirmed lupus genes are opening new avenues of research at the Oklahoma Medical Research Foundation.

Genetics created Mar 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists find protein that reins in runaway network

Marked for death with molecular tags that act like a homing signal for a cell's protein-destroying machinery, a pivotal enzyme is rescued by another molecule that sweeps the telltale targets off in the nick of time.

Medical research created Jan 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

A physician's guide for anti-vaccine parents

In the limited time of an office visit, how can a primary care physician make the case to parents that their child should be vaccinated? During National Infant Immunization Week, a Mayo Clinic vaccine expert and a pediatrician ...

Immunology created Apr 23, 2012 | popularity 3 / 5 (2) | comments 1


Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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