Diseases, Conditions, Syndromes

Video: What does it mean to have an enlarged prostate?

An enlarged prostate, known as benign prostatic hyperplasia (BPH), is a common condition often associated with the natural aging process in men. Dr. Scott Cheney, a Mayo Clinic urologist, says it's a condition where the prostate ...

Health

Poor sleep tied to urinary, prostate symptoms

Poor sleep quality is associated with an increased prevalence of lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH), according to a study published online Oct. 24 in Frontiers in Aging Neuroscience.

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Benign prostatic hyperplasia (BPH) also known as benign prostatic hypertrophy (technically a misnomer), benign enlargement of the prostate (BEP), and adenofibromyomatous hyperplasia, refers to the increase in size of the prostate.

Properly, BPH involves hyperplasia rather than hypertrophy, but the nomenclature is often interchangeable, even amongst urologists. It involves hyperplasia of prostatic stromal and epithelial cells, resulting in the formation of large, fairly discrete nodules in the periurethral region of the prostate. When sufficiently large, the nodules compress the urethral canal to cause partial, or sometimes virtually complete, obstruction of the urethra, which interferes with the normal flow of urine. It leads to symptoms of urinary hesitancy, frequent urination, dysuria (painful urination), increased risk of urinary tract infections, and urinary retention. Although prostate specific antigen levels may be elevated in these patients because of increased organ volume and inflammation due to urinary tract infections, BPH is not considered to be a premalignant lesion.

Adenomatous prostatic growth is believed to begin at approximately age 30 years. An estimated 50% of men have histologic evidence of BPH by age 50 years and 75% by age 80 years. In 40-50% of these patients, BPH becomes clinically significant.

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