Genetics

Researchers create mutant mice to study bipolar disorder

Bipolar disorder (BD) is a debilitating condition characterized by alternating states of depression (known as depressive episodes) and abnormal excitement or irritability (known as manic episodes). Large-scale genome-wide ...

Medications

Could antidepressants cause treatment-emergent mania?

In a study published in Molecular Psychiatry, Mark Frye, M.D., a Mayo Clinic researcher and collaborators, investigated the risk of treatment-emergent mania in bipolar disorder when treated with antidepressants.

Genetics

Genetic risk scores tied to psychiatric diagnostic trajectories

Genetic risk factors for major depression (MD), bipolar disorder (BD), other nonaffective psychosis (ONAP), and schizophrenia are systematically associated with their diagnostic trajectories, according to a study published ...

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