Blood Clots

Uncovering cardiovascular disease genetics

February is American Heart Month, a great time to take a closer look at cardiovascular disease (CVD). According to the World Health Organization (WHO), about 17.5 million people die each year from CVD, a figure representing ...

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A thrombus (Greek θρόμβος), or blood clot, is the final product of the blood coagulation step in hemostasis. It is achieved via the aggregation of platelets that form a platelet plug, and the activation of the humoral coagulation system (i.e. clotting factors). A thrombus is normal in cases of injury, but pathologic in instances of thrombosis.

Mural thrombi are thrombi adherent to the vessel wall. They are not occlusive and affect large vessels, such as heart and aorta. Grossly they appear grey-red with alternating light and dark lines (lines of Zahn) which represent bands of fibrin (darker) with entrapped white blood cells and red blood cells (lighter).

This text uses material from Wikipedia licensed under CC BY-SA

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