Bone Marrow Failure
Alcohol by-product destroys blood stem cells
(Medical Xpress)—Scientists at the Medical Research Council (MRC) Laboratory of Molecular Biology have found that stem cells in the body's 'blood cell factory'—the bone marrow—are extremely sensitive to the main breakdown ...
Medical research
Aug 27, 2012 |
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Researchers discover gene defect that predisposes people to leukemia
A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts ...
Genetics
Sep 04, 2011 |
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Researcher pieces together AML prognosis puzzle
When patients suffering from Acute Myeloid Leukemia (AML) express high levels of the gene, MN1, an already aggressive leukemia is accelerated and shortens survival time. While that's a known fact, the mechanisms involved ...
Cancer
Oct 15, 2012 |
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Researchers find novel predictor for MDS progression risk
Researchers at Moffitt Cancer Center and colleagues have discovered that changes in the physical characteristics of the effector memory regulatory T cell can predict the progression risk of myelodysplastic syndromes (MDS) ...
Immunology
Sep 13, 2012 |
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Collaboration finds kidney disease tied to DNA damage
(Medical Xpress) -- A research collaboration involving Rockefeller University and more than two dozen other institutions has found a link between a gene mutation and chronic kidney failure. The study, published ...
Genetics
Aug 09, 2012 |
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Myelodysplastic syndrome treated with deferasirox shows beneficial iron reduction
Researchers at Moffitt Cancer Center and colleagues at six other institutions have recently tested a treatment for patients with myelodysplastic syndrome, or MDS, a blood-related malignancy that involves the ineffective production ...
Cancer
Jun 22, 2012 |
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Cell signaling discovery provides new hope for blood disorders
Walter and Eliza Hall Institute scientists have revealed new details about how cell signalling is controlled in the immune system, identifying in the process potential new therapeutic targets for treating severe blood disorders.
Medical research
Feb 16, 2012 |
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Key cause of bone marrow failure identified
(Medical Xpress) -- Researchers funded by Leukaemia & Lymphoma Research and the Medical Research Council (MRC) have identified one of the first steps that can cause bone marrow failure and eventually lead to blood cancers. ...
Medical research
May 03, 2011 |
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Team creates a unique mouse model for the study of aplastic anaemia
Aplastic anaemia is characterised by a reduction in the number of the bone marrow cells that go on to form the different cell types present in blood (essentially red blood cells, white blood cells and platelets). In most ...
Medical research
Aug 29, 2012 |
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Stabilizing Fanconi anemia with antioxidants
Fanconi anemia (FA) is a rare genetic disorder which affects one person in 350,000. People affected by this disease have defects in DNA repair, and are hypersensitive to oxidative damage, resulting in bone marrow failure ...
Diseases, Conditions, Syndromes
May 15, 2012 |
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Standard aplastic anemia therapy improves patient outcomes better than newer version
A comparison clinical study of two aplastic anemia treatments found that ATGAM, currently the only licensed aplastic anemia drug in the United States, improved blood cell counts and survival significantly more than did Thymoglobulin, ...
Medical research
Aug 04, 2011 |
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Bone marrow failure occurs in individuals who produce an insufficient amount of red blood cells, white blood cells or platelets. Red blood cells determine how much oxygen needs to be distributed throughout the body’s tissue. White blood cells are constantly helping fight off germs and infections that enter the body. Bone marrow contains platelets, which clot then helps stop the blood flow when a wound occurs.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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