Breast Cancer
Gene expression test distinguishes btw breast cancer patients at high and low risk of late recurrence
A test that measures the expression levels of 58 genes in oestrogen receptor-positive breast cancers can effectively differentiate between patients who are at higher and lower risk for having their cancer recur elsewhere ...
Cancer
May 02, 2013 |
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Study confirms everolimus can overcome trastuzumab resistance in HER-2 positive early breast cancer
A study that aimed to understand how the cancer drug everolimus helps overcome the resistance breast cancers can develop to trastuzumab has left researchers contemplating a puzzle.
Cancer
May 02, 2013 |
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Study opens new prospects for developing new targeted therapies for breast cancer
A study led by prominent breast cancer experts from Europe and the US has revealed a number of potentially important prospects for targeted therapies, and brings opportunities of truly personalised therapy for breast cancer ...
Cancer
May 02, 2013 |
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Genetic and clinical factors best to predict late recurrence in estrogen receptor POS breast cancer
A new analysis has provided a comprehensive comparison of scores designed to predict which women with oestrogen-receptor positive breast cancer are at high risk of recurrence beyond five years after diagnosis, and may benefit ...
Cancer
May 02, 2013 |
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Study reveals magnitude of variation in gene expression measurements within breast cancers
An important new study has revealed the clearest picture yet of precisely how much measurement variation influences gene expression profiles of breast cancer.
Cancer
May 02, 2013 |
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Breast cancer heterogeneity no barrier to predictive testing, study shows
Breast cancers contain many different cell types with different patterns of gene expression, but a new study provides reassurance that this variability should not be a barrier to using gene expression tests to help tailor ...
Cancer
May 02, 2013 |
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Genomics to reshape endometrial cancer treatment
The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.
Cancer
May 01, 2013 |
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Cosmetic breast implants may adversely affect survival in women who develop breast cancer
Cosmetic breast implants seem to adversely affect the survival of women who are subsequently diagnosed with breast cancer, finds a small study published on BMJ website today.
Cancer
Apr 30, 2013 |
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Comprehensive analysis supports SERMs for cutting breast cancer
(HealthDay)—Treatment with selective estrogen receptor modulators (SERMs) is associated with a significant reduction in the incidence of breast cancer, especially for the first five years after treatment, ...
Cancer
Apr 30, 2013 |
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Decoded: Molecular messages that tell prostate and breast cancers to spread
Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain ...
Cancer
Apr 30, 2013 |
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Researcher examines behavior of genes to understand breast cancer risks, other health issues
Most often, people associate circadian rhythms with the symptoms of jet lag that occur after crossing several time zones. Circadian rhythms, which get their cues from light and darkness, can change sleep-wake ...
Medical research
Apr 30, 2013 |
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New guidelines suggest HIV screening for all adults
(HealthDay)—New guidelines from the U.S. Preventive Services Task Force call for virtually every adult to be routinely screened for HIV, the virus that causes AIDS.
HIV & AIDS
Apr 29, 2013 |
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Cancer research often falls short: study
Cancer research tends to involve small studies focused on a single therapy, often falling short of scientific standards seen in other medical investigations, said a study released Monday.
Cancer
Apr 29, 2013 |
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Big data analysis identifies prognostic RNA markers in a common form of breast cancer
A Big Data analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer.
Cancer
Apr 29, 2013 |
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Postcode inequality for cancer diagnosis 'costs lives'
Hundreds of women with breast cancer living in England's most deprived areas would have better survival rates if they were diagnosed at the same stage as those who lived in affluent areas.
Cancer
Apr 29, 2013 |
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1
Breast cancer (malignant breast neoplasm) is a type of cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk. Cancers originating from ducts are known as ductal carcinomas; those originating from lobules are known as lobular carcinomas. Breast cancer is a disease of humans and other mammals; while the overwhelming majority of cases in humans are women, men can sometimes also develop breast cancer.
The size, stage, rate of growth, and other characteristics of the tumor determine the kinds of treatment. Treatment may include surgery, drugs (hormonal therapy and chemotherapy), radiation and/or immunotherapy. Surgical removal of the tumor provides the single largest benefit, with surgery alone being capable of producing a cure in many cases. To somewhat increase the likelihood of long-term disease-free survival, several chemotherapy regimens are commonly given in addition to surgery. Most forms of chemotherapy kill cells that are dividing rapidly anywhere in the body, and as a result cause temporary hair loss and digestive disturbances. Radiation is indicated especially after breast conserving surgery and substantially improves local relapse rates and in many circumstances also overall survival. Some breast cancers are sensitive to hormones such as estrogen and/or progesterone, which makes it possible to treat them by blocking the effects of these hormones.
Worldwide, breast cancer comprises 22.9% of all cancers (excluding non-melanoma skin cancers) in women. In 2008, breast cancer caused 458,503 deaths worldwide (13.7% of cancer deaths in women). Breast cancer is more than 100 times more common in women than breast cancer in men, although males tend to have poorer outcomes due to delays in diagnosis.
Prognosis and survival rate varies greatly depending on cancer type, staging and treatment. However, survival rates across the world are generally good. Overall more than 8 out of 10 women (84%) in England that are diagnosed with the disease survive it for at least 5 years.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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