Cholera

Discovery could reduce chemotherapy's side effects

A team of researchers at Duke University has determined the structure of a key molecule that can carry chemotherapy and anti-viral drugs into cells, which could help to create more effective drugs with fewer effects to healthy ...

Mar 11, 2012
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Array of light for early disease detection?

A special feature in this week's issue of the journal Science highlights protein array technology, touching on research conducted by Joshua LaBaer, director of the Biodesign Institute's Virginia G. Piper ...

May 22, 2012
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Cholera is an infection of the small intestine caused by the bacterium Vibrio cholerae. The main symptoms are profuse, watery diarrhea and vomiting. Transmission occurs primarily by drinking water or eating food that has been contaminated by the feces of an infected person (even an asymptomatic one). The severity of the diarrhea and vomiting can lead to rapid dehydration and electrolyte imbalance, and death in some cases. The primary treatment is with oral rehydration solution (ORS) to replace water and electrolytes; if this is not tolerated or does not provide quick enough treatment, intravenous fluids can also be used. Antibiotics are beneficial in those with severe disease to shorten its duration and severity. Worldwide, it affects 3–5 million people and causes 100,000–130,000 deaths a year as of 2010[update]. Cholera was one of the earliest infections to be studied by epidemiological methods.

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