Chronic Alcoholism

Heavy drinking rewires brain, increasing susceptibility to anxiety problems

Doctors have long recognized a link between alcoholism and anxiety disorders such as post-traumatic stress disorder (PTSD). Those who drink heavily are at increased risk for traumatic events like car accidents and domestic ...

Neuroscience created Sep 02, 2012 | popularity 4.5 / 5 (4) | comments 2 | with audio podcast

Drinking alcohol shrinks critical brain regions in genetically vulnerable mice

Brain scans of two strains of mice imbibing significant quantities of alcohol reveal serious shrinkage in some brain regions - but only in mice lacking a particular type of receptor for dopamine, the brain's "reward" chemical. ...

Medical research created Feb 15, 2012 | popularity not rated yet | comments 0 | with audio podcast

New research shows weekend binge drinking could leave lasting liver damage

Long after a hangover, a night of bad decisions might take a bigger toll on the body than previously understood. Described in the current issue of Alcoholism: Clinical & Experimental Research, a study at the University of Missouri has revealed a ...

Health created May 01, 2013 | popularity not rated yet | comments 0

Chronic alcohol and marijuana use during youth can compromise white-matter integrity

Chronic use of alcohol and marijuana during youth is associated with poorer neural structure, function, and metabolism, as well as worsened neurocognitive abilities into later adolescence and adulthood. This may be due to ...

Addiction created Dec 14, 2012 | popularity not rated yet | comments 6 | with audio podcast

Alcohol impairs the body's ability to fight off viral infection

Alcohol is known to worsen the effects of disease, resulting in longer recovery period after trauma, injury or burns. It is also known to impair the anti-viral immune response, especially in the liver, including response ...

Health created Sep 30, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers find that alcohol consumption damages brain's support cells

Alcohol consumption affects the brain in multiple ways, ranging from acute changes in behavior to permanent molecular and functional alterations. The general consensus is that in the brain, alcohol targets mainly neurons. ...

Neuroscience created Mar 18, 2013 | popularity 3 / 5 (1) | comments 0

Wiping memories to tackle alcoholism

(Medical Xpress) -- Researchers at the University of Cambridge believe connections developed in the brain between the ‘drug high’ of alcohol and the situations in which it’s used create loaded ...

Psychology & Psychiatry created Mar 13, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

First guidelines for brain amyloid imaging in Alzheimer's released

Only recently has it become possible to create high-quality images of the brain plaques characteristic of Alzheimer's disease in living people through positron emission tomography (PET). Even so, questions remain about what ...

Alzheimer's disease & dementia created Jan 28, 2013 | popularity not rated yet | comments 0

Alcoholic men demonstrate a deficit in empathy and distorted view of irony

Emotions are often implicit undertones to our communication interactions, and decoding them requires substantial social and cognitive abilities. Prior research has shown that chronic alcoholics often demonstrate impaired ...

Addiction created Nov 08, 2012 | popularity 5 / 5 (1) | comments 0

Researchers uncover gender differences in the effects of long-term alcoholism

Researchers from Boston University School of Medicine (BUSM) and Veterans Affairs (VA) Boston Healthcare System have demonstrated that the effects on white matter brain volume from long-term alcohol abuse are different for ...

Addiction created Aug 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Binge drinking can dramatically amplify damage to the liver

Alcoholic liver disease (ALD) is characterized by a fatty liver, hepatitis, fibrosis, and cirrhosis. Binge drinking is on the rise worldwide, and is particularly common in the U.S. A review of studies addressing the effects ...

Addiction created Jan 22, 2013 | popularity not rated yet | comments 0

Math can save Tylenol overdose patients

University of Utah mathematicians developed a set of calculus equations to make it easier for doctors to save Tylenol overdose patients by quickly estimating how much painkiller they took, when they consumed ...

Medical research created Feb 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

Alcoholism's short-term effects on memory functioning are harmful

Alcoholism can disrupt memory functioning well before incurring the profound amnesia of Korsakoff's syndrome. For example, associative memory – used in remembering face-name associations – can be impaired in alcoholics. ...

Addiction created Apr 16, 2012 | popularity not rated yet | comments 0

Combination of 2 drugs reverses liver tumors

The combination of two inhibitors of protein mTOR stops the growth of primary liver cancer and destroys tumour cells, according to a study by researchers of the Group of Metabolism and Cancer at Bellvitge Biomedical Research ...

Medications created May 02, 2012 | popularity not rated yet | comments 0

Recovery of brain volumes with abstinence may vary for different brain regions

Chronic alcohol abuse can severely damage the nervous system, particularly cognitive functions, cerebral metabolism, and brain morphology. Building upon previous findings that alcoholics can experience brain volume recovery ...

Addiction created Oct 16, 2012 | popularity not rated yet | comments 0


Alcoholism is a broad term for problems with alcohol, and is generally used to mean compulsive and uncontrolled consumption of alcoholic beverages, usually to the detriment of the drinker's health, personal relationships, and social standing. It is medically considered a disease, specifically a neurological disorder, and in medicine several other terms are used, specifically "alcohol abuse" and "alcohol dependence" which have more specific definitions. In 1979 an expert World Health Organization committee discouraged the use of "alcoholism" in medicine, preferring the category of "alcohol dependence syndrome". In the 19th and early 20th centuries, alcohol dependence in general was called dipsomania, but that term now has a much more specific meaning. People suffering from alcoholism are often called "alcoholics". Many other terms, some of them insulting or informal, have been used throughout history. The World Health Organization estimates that there are 140 million people with alcoholism worldwide.

Alcoholism is called a "dual disease" since it includes both mental and physical components. The biological mechanisms that cause alcoholism are not well understood. Social environment, stress, mental health, family history, age, ethnic group, and gender all influence the risk for the condition. Long-term alcohol abuse produces changes in the brain's structure and chemistry such as tolerance and physical dependence. These changes maintain the person with alcoholism's compulsive inability to stop drinking and result in alcohol withdrawal syndrome if the person stops. Alcohol damages almost every organ in the body, including the brain. The cumulative toxic effects of chronic alcohol abuse can cause both medical and psychiatric problems.

Identifying alcoholism is difficult because of the social stigma associated with the disease that causes people with alcoholism to avoid diagnosis and treatment for fear of shame or social consequences. The evaluation responses to a group of standardized questioning is a common method for diagnosing alcoholism. These can be used to identify harmful drinking patterns, including alcoholism. In general, problem drinking is considered alcoholism when the person continues to drink despite wanting to stop because of social or health problems caused by drinking.

Treatment of alcoholism takes several steps. Because of the medical problems that can be caused by withdrawal, alcohol detoxification is carefully controlled and may involve medications such as benzodiazepines such as diazepam (Valium). People with alcoholism also sometimes have other addictions, including addictions to benzodiazepines, which may complicate this step. After detoxification, other support such as group therapy or self-help groups are used to help the person remain sober. Thombs (1999) states according to behavioural sciences alcoholism is described as a “maladaptive behaviour”. He explains this must not be confused with “misbehaviour”. Behavioural scientists explain that addicts have a behaviour pattern that may lead to destructive consequences for themselves, their families and society. This does not label addicts as bad or irresponsible. Compared with men, women are more sensitive to alcohol's harmful physical, cerebral, and mental effects.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Latest Spotlight News

Controlling mood through the motions of mitochondria

(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...

Motion quotient: IQ predicted by ability to filter motion (w/ video)

A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...

Multiple research teams unable to confirm high-profile Alzheimer's study

Teams of highly respected Alzheimer's researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science.

Scientists discover molecule triggers sensation of itch

Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as ...

Researchers find common childhood asthma unconnected to allergens or inflammation

Little is known about why asthma develops, how it constricts the airway or why response to treatments varies between patients. Now, a team of researchers at Weill Cornell Medical College, Columbia University Medical Center ...

Diabetes' genetic underpinnings can vary based on ethnic background, studies say

Ethnic background plays a surprisingly large role in how diabetes develops on a cellular level, according to two new studies led by researchers at the Stanford University School of Medicine.

Study reveals new mechanism for estrogen suppression of liver lipid synthesis

By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.

Scientists discover cinnamon compounds' potential ability to prevent Alzheimer's

Cinnamon: Can the red-brown spice with the unmistakable fragrance and variety of uses offer an important benefit? The common baking spice might hold the key to delaying the onset of –– or warding off ...

Ferrets, pigs susceptible to H7N9 avian influenza virus

Chinese and U.S. scientists have used virus isolated from a person who died from H7N9 avian influenza infection to determine whether the virus could infect and be transmitted between ferrets. Ferrets are often used as a mammalian ...

When oxygen is short, EGFR prevents maturation of cancer-fighting miRNAs

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs (miRNAs) before it's dissolved, researchers ...