Chronic Autoimmune Disease
Study identifies biomarker and potential therapy target in multiple sclerosis
Researchers from Benaroya Research Institute at Virginia Mason (BRI) have found that proteins in the IL-6 signaling pathway may be leveraged as novel biomarkers of multiple sclerosis (MS) to gauge disease activity and as ...
Immunology
Jan 30, 2013 |
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Newly approved oral medication slows rheumatoid arthritis joint damage
A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis (RA) patients who did not respond to methotrexate (MTX). Results of the 12-month ...
Arthritis & Rheumatism
Jan 24, 2013 |
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Researchers implicate well-known protein in fibrosis
An international multi-disciplinary research team led by Northwestern Medicine scientists has uncovered a new role for the protein toll-like receptor 4 (TLR4) in the development of tissue fibrosis, or scarring.
Medical research
Nov 20, 2012 |
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No difference in death rates among patients exposed to common rheumatoid arthritis drugs
New research confirms no significant difference in the rates of death among patients with rheumatoid arthritis (RA) who were exposed to one of several TNF inhibitors used to treat RA, adalimumab (Humira), etanercept (Enbrel), ...
Arthritis & Rheumatism
Aug 08, 2012 |
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Cancer screening rates comparable for those with and without rheumatoid arthritis
New research reveals that rheumatoid arthritis (RA) patients do not receive fewer cancer screening tests than the general population. Results of the study, funded in part by grants from the National Institutes of Health (NIH) ...
Arthritis & Rheumatism
Jul 10, 2012 |
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Strides made in diagnosing, treating lupus
(HealthDay) -- Sometimes it takes years for people to get diagnosed with lupus. That wasn't the case for Marisa Zeppieri-Caruana, who had so many of the classic systemic lupus erythematosus symptoms -- such ...
Immunology
May 10, 2012 |
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The American College of Rheumatology issues guidelines for management of lupus nephritis
The American College of Rheumatology (ACR) has issued newly created guidelines for the screening, treatment, and management of lupus nephritis—a severe manifestation of systemic lupus erythematosus (SLE) where the disease ...
Diseases, Conditions, Syndromes
May 03, 2012 |
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Study discovers three new lupus genes
Three newly confirmed lupus genes are opening new avenues of research at the Oklahoma Medical Research Foundation.
Genetics
Mar 29, 2012 |
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New genetic path for scleroderma: Patient biopsies reveal potential new target for therapy
A genetic pathway previously known for its role in embryonic development and cancer has been identified as a target for systemic sclerosis, or scleroderma, therapy. The finding, discovered by a cross-disciplinary team led ...
Arthritis & Rheumatism
Mar 19, 2012 |
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Women with rheumatoid arthritis and lupus give birth to fewer children
New research shows that more than half of women with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) have fewer children than desired. While patient choice has some influence on the smaller family size, findings ...
Arthritis & Rheumatism
Feb 16, 2012 |
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Northwestern to explore personalized medicine for scleroderma
Northwestern Medicine researchers have received two five-year grants totaling $953,000 from the National Institutes of Health's (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases to study scleroderma, ...
Diseases, Conditions, Syndromes
Dec 02, 2011 |
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Most lupus nephritis patients with end-stage renal disease opt for hemodialysis therapy
Newly published research shows that more patients with end-stage renal disease (ESRD) caused by lupus nephritis choose hemodialysis as their initial kidney replacement therapy over peritoneal dialysis and preemptive kidney ...
Diseases, Conditions, Syndromes
Nov 07, 2011 |
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New drug shows promise against multiple sclerosis
An experimental drug called Ocrelizumab has shown promise in a Phase 2 clinical trial involving 220 people with multiple sclerosis (MS), an often debilitating, chronic autoimmune disease that affects an increasing number ...
Neuroscience
Nov 01, 2011 |
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Researcher says banned pregnancy drug impacts fetal immune system
(Medical Xpress) -- A synthetic estrogen—diethylstilbestrol (DES)—prescribed to women in the 1940s, 1950s, and 1960s to prevent miscarriages had serious, untoward effects in daughters of these women, including the ...
Medications
Oct 18, 2011 |
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Continued treatment for lupus may boost survival of those patients with end-stage kidney disease
Researchers at Albert Einstein College of Medicine of Yeshiva University have shown that close supervision by rheumatologists and the use of immunosuppressant drugs improve the survival of lupus patients with end-stage kidney ...
Diseases, Conditions, Syndromes
Sep 20, 2011 |
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Latest Spotlight News
New immune system discovered
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
Brain can be trained in compassion, study shows
Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.
Do salamanders hold the solution to regeneration?
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
Hormone levels may provide key to understanding psychological disorders in women
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
Multiple research teams unable to confirm high-profile Alzheimer's study
Teams of highly respected Alzheimer's researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science.
The compound in the Mediterranean diet that makes cancer cells 'mortal'
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
Brain uses internal 'average voice' prototype to identify who is talking
(Medical Xpress)—The human brain is able to identify individuals' voices by comparing them against an internal 'average voice' prototype, according to neuroscientists.
Motion quotient: IQ predicted by ability to filter motion (w/ video)
A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose ...
Controlling mood through the motions of mitochondria
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...
Slowing the aging process—only with antibiotics
Swiss scientists reveal the mechanism responsible for aging hidden deep within mitochondria—and dramatically slow it down in worms by administering antibiotics to the young.
