Chronic Fatigue Syndrome

How muscle fatigue originates in the head

The extent to which we are able to activate our muscles voluntarily depends on motivation and will power or the physical condition and level of fatigue of the muscles, for instance. The latter particularly ...

Dec 05, 2011
popularity 5 / 5 (2) | comments 0 | with audio podcast

Chronic fatigue syndrome (CFS) is the most common name used to designate a significantly debilitating medical disorder or group of disorders generally defined by persistent fatigue accompanied by other specific symptoms for a minimum of six months, not due to ongoing exertion, not substantially relieved by rest, nor caused by other medical conditions. The disorder may also be referred to as myalgic encephalomyelitis (ME), post-viral fatigue syndrome (PVFS), chronic fatigue immune dysfunction syndrome (CFIDS), or several other terms. Biological, genetic, infectious and psychological mechanisms have been proposed for the development and persistence of symptoms but the etiology of CFS is not understood and may have multiple causes. There is no diagnostic laboratory test or biomarker for CFS.

Symptoms of CFS include post-exertional malaise; unrefreshing sleep; widespread muscle and joint pain; sore throat; headaches of a type not previously experienced; cognitive difficulties; chronic, often severe, mental and physical exhaustion; and other characteristic symptoms in a previously healthy and active person. Persons with CFS may report additional symptoms including muscle weakness, increased sensitivity to light, sounds and smells, orthostatic intolerance, digestive disturbances, depression, and cardiac and respiratory problems. It is unclear if these symptoms represent co-morbid conditions or are produced by an underlying etiology of CFS.

Fatigue is a common symptom in many illnesses, but CFS is comparatively rare. Estimates of CFS prevalence vary widely, from 7 to 3,000 cases of CFS for every 100,000 adults, but national health organizations have estimated more than 1 million Americans and approximately a quarter of a million people in the UK have CFS. CFS occurs more often in women than men, and is less prevalent among children and adolescents. The quality of life is "particularly and uniquely disrupted" in CFS.

There is agreement on the genuine threat to health, happiness and productivity posed by CFS, but various physicians' groups, researchers and patient advocates promote different nomenclature, diagnostic criteria, etiologic hypotheses and treatments, resulting in controversy about many aspects of the disorder. The name "chronic fatigue syndrome" itself is controversial as many patients and advocacy groups, as well as some experts, believe the name trivializes the medical condition and want the name changed.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Wireless subretinal prostheses allows blind mice to see light

(Medical Xpress)—A team of researchers from the U.S. and Scotland has developed a new type of retinal prostheses designed to restore sight to blind patients. In their paper published in the journal Nature Co ...

Laughing gas does not increase heart attacks

(Medical Xpress)—Nitrous oxide—best known as laughing gas—is one of the world's oldest and most widely used anesthetics. Despite its popularity, however, experts have questioned its impact on the risk ...

Model recreates wear and tear of osteoarthritis

(Medical Xpress)—There's a reason osteoarthritis is often called wear-and-tear arthritis: Repeated stress on joints over time results in degeneration of the soft cartilage that normally distributes loads ...

Review of research calls into question sex differences in face-to-face mate preferences

Women say they place a priority on a potential partner's earning prospects, and men claim to value a potential partner's physical attractiveness; these sex differences have been widely studied by psychologists for decades.

Study of vocal impersonations reveals how we manipulate our voices

A study of vocal impersonations has shown for the first time how speech production and voice perception systems in the brain interact to influence the way our voices sound. The research, supported by the ...

Researchers pinpoint how smoking causes osteoporosis

(Medical Xpress)—Human bone breaks down and regenerates naturally all the time, in a perfectly balanced dance that maintains skeletal integrity.

New paper offers insights into how cancer cells avoid cell death

(Medical Xpress)—A new study by a team of researchers from the University of Notre Dame provides an important new insight into how cancer cells are able to avoid the cell death process. The findings may ...

Study shows cultural images may hinder proficiency in second language skills

(Medical Xpress)—A team of combined researchers from Columbia Business School and Singapore Management University has found that people who have learned a second language become less proficient at speaking ...

Key protein is linked to circadian clocks, helps regulate metabolism

Inside each of us is our own internal timing device. It drives everything from sleep cycles to metabolism, but the inner-workings of this so-called "circadian clock" are complex, and the molecular processes behind it have ...

The discerning fruit fly: Linking brain-cell activity and behavior in smell recognition

Behind the common expression "you can't compare apples to oranges" lies a fundamental question of neuroscience: How does the brain recognize that apples and oranges are different? A group of neuroscientists ...