Genetics

Epigenetic profiling identifies potential COPD treatment targets

Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease). Using high-resolution epigenetic profiling, German and British scientists ...

Diseases, Conditions, Syndromes

Study linking mucus plugs and COPD mortality could help save lives

A retrospective analysis of patient data from the COPDGene study suggests that targeting mucus plugs could help prevent deaths from chronic obstructive pulmonary disease—the fourth leading cause of death in the United States

Medical economics

Global burden of chronic respiratory diseases quantified

Chronic respiratory diseases (CRDs) were the third leading cause of death globally, accounting for 4.0 million deaths in 2019, according to a study published online April 25 in eClinicalMedicine.

Genetics

COPDGene study follows emphysema patients over 10 years

Researchers at National Jewish Health evaluating computerized tomography (CT) scans of emphysema progression in the COPDGene study showed that, during a span of 10 years, participants with pre-existing emphysema who continued ...

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