Chronic Obstructive Pulmonary Disease

Study finds inhibitor for COPD lung destruction

In a new study, a research team based at Brown and Yale implicates a specific mitochondrial protein and pathway in the development of chronic obstructive pulmonary disease (COPD) from exposure to cigarette smoke. Observations ...

May 04, 2015
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Finding points to a cause of chronic lung disease

Scientists have long suspected that respiratory viruses—the sort that cause common colds or bronchitis—play a critical role in the long-term development of chronic lung diseases such as asthma and chronic obstructive ...

Apr 21, 2015
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Review: Opioids reduce breathlessness in COPD

(HealthDay)—In chronic obstructive pulmonary disease (COPD), opioids can improve breathlessness, but not exercise capacity, according to a review published online March 24 in the Annals of the American Thoracic Society.

Apr 03, 2015
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Outcomes vary with transcatheter valve surgery

(HealthDay)—Of more than 12,000 patients who underwent transcatheter aortic valve replacement, nearly one-quarter died within a year, while roughly 4 percent had a stroke, new research reveals. However, almost half who ...

Mar 11, 2015
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Chronic obstructive pulmonary disease (COPD), also known as chronic obstructive lung disease (COLD), chronic obstructive airway disease (COAD), chronic airflow limitation (CAL) and chronic obstructive respiratory disease (CORD), is the co-occurrence of chronic bronchitis and emphysema, a pair of commonly co-existing diseases of the lungs in which the airways become narrowed. This leads to a limitation of the flow of air to and from the lungs, causing shortness of breath (dyspnea). In clinical practice, COPD is defined by its characteristically low airflow on lung function tests. In contrast to asthma, this limitation is poorly reversible and usually gets progressively worse over time. In England, an estimated 842,100 of 50 million people have a diagnosis of COPD.

COPD is caused by noxious particles or gas, most commonly from tobacco smoking, which triggers an abnormal inflammatory response in the lung.

The diagnosis of COPD requires lung function tests. Important management strategies are smoking cessation, vaccinations, rehabilitation, and drug therapy (often using inhalers). Some patients go on to require long-term oxygen therapy or lung transplantation.

Worldwide, COPD ranked as the sixth leading cause of death in 1990. It is projected to be the fourth leading cause of death worldwide by 2030 due to an increase in smoking rates and demographic changes in many countries. COPD is the third leading cause of death in the U.S. and the economic burden of COPD in the U.S. in 2007 was $42.6 billion in health care costs and lost productivity.

This text uses material from Wikipedia licensed under CC BY-SA

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