Colorectal Cancer

Gut microbes spur development of bowel cancer

It is not only genetics that predispose to bowel cancer; microbes living in the gut help drive the development of intestinal tumors, according to new research in mice published in the March issue of The Jo ...

Mar 03, 2014
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Genomics to reshape endometrial cancer treatment

The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.

May 01, 2013
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Three new genetic links to colorectal cancer

Vanderbilt-Ingram Cancer Center investigators have identified three new genetic "hotspots" linked to colorectal cancer. These variants, reported Dec. 23 in an Advanced Online Publication in Nature Genetics, provide new in ...

Dec 23, 2012
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Obesity may shorten colon cancer survival

(HealthDay)—Colon cancer patients who were obese before their diagnosis may have an increased risk of dying from their cancer and other causes, a new study finds.

Apr 09, 2014
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Study links coffee to lower liver cancer risk

(HealthDay)—Researchers say they've discovered yet another reason to love coffee: A new study suggests that people who drink at least a cup a day have a lower risk of liver cancer compared to those who ...

Apr 09, 2014
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Bacterial gut biome may guide colon cancer progression

Colorectal cancer develops in what is probably the most complex environment in the human body, a place where human cells cohabitate with a colony of approximately 10 trillion bacteria, most of which are unknown. At the 2014 ...

Apr 04, 2014
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Colorectal cancer, commonly known as bowel cancer, is a cancer from uncontrolled cell growth in the colon, rectum, or appendix. Symptoms typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.

Most colorectal cancer occurs due to lifestyle and increasing age with only a minority of cases associated with underlying genetic disorders. It typically starts in the lining of the bowel and if left untreated, can grow into the muscle layers underneath, and then through the bowel wall. Screening is effective at decreasing the chance of dying from colorectal cancer and is recommended starting at the age of 50 and continuing until a person is 75 years old. Localized bowel cancer is usually diagnosed through sigmoidoscopy or colonoscopy.

Cancers that are confined within the wall of the colon are often curable with surgery while cancer that has spread widely around the body is usually not curable and management then focuses on extending the person's life via chemotherapy and improving quality of life. Colorectal cancer is the fourth most commonly diagnosed cancer in the world, but it is more common in developed countries. Around 60% of cases were diagnosed in the developed world. It is estimated that worldwide, in 2008, 1.23 million new cases of colorectal cancer were clinically diagnosed, and that it killed 608,000 people.

This text uses material from Wikipedia licensed under CC BY-SA

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