Cushing Disease

Plant extract fights brain tumour

Silibinin has an outstanding safety profile in humans and is currently used for the treatment of liver disease and poisoning. Scientists at the Max Planck Institute of Psychiatry in Munich discovered in collaboration with ...

Feb 10, 2015
popularity4358 comments 1

A disease of mistaken identity

The symptoms of Cushing disease are unmistakable to those who suffer from it – excessive weight gain, acne, distinct colored stretch marks on the abdomen, thighs and armpits, and a lump, or fat deposit, on the back of the ...

Jun 23, 2014
popularity0 comments 0

Cushing's syndrome is a hormone disorder caused by high levels of cortisol in the blood. This can be caused by taking glucocorticoid drugs, or by tumors that produce cortisol or adrenocorticotropic hormone (ACTH) or CRH.

Cushing's disease refers to one specific cause of the syndrome: a tumor (adenoma) in the pituitary gland that produces large amounts of ACTH, which in turn elevates cortisol. It is the most common cause of Cushing's syndrome, responsible for 70% of cases excluding glucocorticoid related cases.

This pathology was described by Harvey Cushing in 1932. The syndrome is also called Itsenko-Cushing syndrome, hyperadrenocorticism or hypercorticism.

Cushing's syndrome is not confined to humans and is also a relatively common condition in domestic dogs and horses. It also occurs in cats, but rarely.

It should not be confused with Cushing's triad, a disease state resulting from increased intracranial pressure.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Runner's high linked to cannabinoid receptors in mice

(Medical Xpress)—A team of researchers from several institutions in Germany has found a link between cannabinoid receptors in mice and what is commonly known as "runner's high." In their paper published in Proceedings of ...

What role does the hippocampus play in memory?

(Medical Xpress)—Meet the hippocampus: A seahorse-shaped structure in the cerebral cortex's medial temporal lobe, it's part of the limbic system, generally believed to be involved in spatial navigation and establishing ...

Snapshot turns T cell immunology on its head

Challenging a universally accepted, longstanding consensus in the field of immunity requires hard evidence. New research from the Australian Research Council Centre of excellence in advanced Molecular imaging has shown the ...