Depression

Closing the loop with optogenetics

An engineering example of closed-loop control is a simple thermostat used to maintain a steady temperature in the home. Without it, heating or air conditioning would run without reacting to changes in outside conditions, ...

4 hours ago
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Is neuroticism fueled by overthinking?

Isaac Newton was a classic neurotic. He was a brooder and a worrier, prone to dwelling on the scientific problems before him as well as his childhood sins. But Newton also had creative breakthroughs—thoughts on physics ...

23 hours ago
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Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behaviour, feelings and physical well-being. Depressed people may feel sad, anxious, empty, hopeless, helpless, worthless, guilty, irritable, or restless. They may lose interest in activities that once were pleasurable, experience loss of appetite or overeating, or problems concentrating, remembering details or making decisions; and may contemplate or attempt suicide. Insomnia, excessive sleeping, fatigue, loss of energy, or aches, pains or digestive problems that are resistant to treatment may be present.

Depressed mood is a normal reaction to certain life events, a symptom of some medical conditions (e.g., Addison's disease, hypothyroidism), various medical treatments (e.g., hepatitis C drug therapy), and a feature of certain psychiatric syndromes.

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Closing the loop with optogenetics

An engineering example of closed-loop control is a simple thermostat used to maintain a steady temperature in the home. Without it, heating or air conditioning would run without reacting to changes in outside conditions, ...