Diabetes Mellitus

Gemigliptin, metformin combo beats monotherapy in T2DM

(HealthDay)—Gemigliptin combined with metformin is superior to monotherapy with either drug for patients with type 2 diabetes mellitus (T2DM), according to a study published online Sept. 13 in Diabetes, Obesity and Metabolism.

Sep 20, 2016
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Black gains in life expectancy

In a Viewpoint published online by JAMA, Victor R. Fuchs, Ph.D., Henry J. Kaiser Professor Emeritus, Stanford University, Stanford, Calif., discusses the narrowing life-expectancy gap between the U.S. black and white populations ...

Sep 22, 2016
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Gender of growing importance in diabetes studies

The international guidelines for the management of type 2 diabetes consider such factors such as age, social environment, the duration of the illness and associated health complaints. But gender is not included. This is becoming ...

Jul 20, 2016
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Diabetes mellitus, often simply referred to as diabetes, is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger).

There are three main types of diabetes:

Other forms of diabetes mellitus include congenital diabetes, which is due to genetic defects of insulin secretion, cystic fibrosis-related diabetes, steroid diabetes induced by high doses of glucocorticoids, and several forms of monogenic diabetes.

All forms of diabetes have been treatable since insulin became available in 1921, and type 2 diabetes may be controlled with medications. Both type 1 and 2 are chronic conditions that usually cannot be cured. Pancreas transplants have been tried with limited success in type 1 DM; gastric bypass surgery has been successful in many with morbid obesity and type 2 DM. Gestational diabetes usually resolves after delivery. Diabetes without proper treatments can cause many complications. Acute complications include hypoglycemia, diabetic ketoacidosis, or nonketotic hyperosmolar coma. Serious long-term complications include cardiovascular disease, chronic renal failure, retinal damage. Adequate treatment of diabetes is thus important, as well as blood pressure control and lifestyle factors such as smoking cessation and maintaining a healthy body weight.

Globally as of 2010 it is estimated that there are 285 million people diabetes with type 2 making up about 90% of the cases.

This text uses material from Wikipedia licensed under CC BY-SA

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