Genetics

Epilepsy gene identified in dogs

Many breeds of dogs are prone to epileptic seizures. Veterinary neurologists and geneticists have now localized the mutation responsible for a specific form of epilepsy in Rhodesian ridgebacks.

Neuroscience

New epilepsy warning device could save thousands of lives

A new high-tech bracelet, developed by scientists from the Netherlands detects 85 percent of all severe night-time epilepsy seizures. That is a much better score than any other technology currently available. The researchers ...

Medications

Anti-seizure medication has a new target

An anti-seizure medication acts on unexpected molecular targets, according to a Northwestern Medicine study published in the Journal of Neuroscience.

Neuroscience

New autism marker discovered in kids

Why do so many children with autism often suffer from epilepsy? Northwestern Medicine scientists have discovered an important brain protein that quiets overactive brain cells and is at abnormally low levels in children with ...

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Epilepsy (from the Ancient Greek ἐπιληψία (epilēpsía) — "seizure") is a common and diverse set of chronic neurological disorders characterized by seizures. Some definitions of epilepsy require that seizures be recurrent and unprovoked, but others require only a single seizure combined with brain alterations which increase the chance of future seizures.

Epileptic seizures result from abnormal, excessive or hypersynchronous neuronal activity in the brain. About 50 million people worldwide have epilepsy, and nearly 90% of epilepsy occurs in developing countries. Epilepsy becomes more common as people age. Onset of new cases occur most frequently in infants and the elderly. As a consequence of brain surgery, epileptic seizures may occur in recovering patients.

Epilepsy is usually controlled, but not cured, with medication. However, over 30% of people with epilepsy do not have seizure control even with the best available medications. Surgery may be considered in difficult cases. Not all epilepsy syndromes are lifelong – some forms are confined to particular stages of childhood. Epilepsy should not be understood as a single disorder, but rather as syndromic with vastly divergent symptoms, all involving episodic abnormal electrical activity in the brain and numerous seizures.

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