Overweight & Obesity

160 million years of life lost to obesity in 2019

Researchers at the National University in Singapore and colleagues in the US and China undertook a two-decade metabolic analysis of Global Burden of Disease (GBD) reports. They have published their findings in the journal ...

Medical research

How gut microbes help mend damaged muscles

The human immune system is incredibly versatile. Among its most skilled multitaskers are T cells, known for their role in everything from fighting infection to reining in inflammation to killing nascent tumors.

Diseases, Conditions, Syndromes

Novel organoid models to study non-alcoholic fatty liver disease

Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology have established novel human organoid models of fatty liver ...

Medical research

Finding the best models for liver and kidney disease

In two separate studies, researchers at EPFL have carried out extensive tests to develop the best mouse models for studying kidney and liver diseases. The findings provide crucial insights into both conditions, and are expected ...

Diseases, Conditions, Syndromes

Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...

Genetics

Trigger for world's most common liver disease identified

University of Virginia School of Medicine researchers have discovered a key trigger for non-alcoholic fatty liver disease, a mysterious condition that causes fat to build up in the liver for no clear reason. The new insights ...

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