Fibrosis

Discovery shows medications can treat inflammation without increasing risk for infection

In a discovery that can fundamentally change how drugs for arthritis, and potentially many other diseases, are made, University of Utah medical researchers have identified a way to treat inflammation while potentially minimizing ...

Inflammatory disorders created Nov 11, 2012 | popularity 4.8 / 5 (9) | comments 0 | with audio podcast

Do salamanders hold the solution to regeneration?

Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...

Medical research created May 20, 2013 | popularity 4.9 / 5 (7) | comments 4 | with audio podcast

Scar findings could lead to new therapies

Researchers at the Stanford University School of Medicine report that they have identified the molecular pathway through which physical force contributes to scarring in mice.

Medical research created Dec 11, 2011 | popularity 5 / 5 (6) | comments 1 | with audio podcast

Scarring cells revert to inactive state as liver heals

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report that significant numbers of myofibroblasts – cells that produce the fibrous ...

Medical research created May 07, 2012 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Scientists identify agent that can block fibrosis of skin, lungs

Researchers at the University of Pittsburgh School of Medicine have identified an agent that in lab tests protected the skin and lungs from fibrosis, a process that can ultimately end in organ failure and even death because ...

Medical research created May 30, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Study shows that blocking an inflammation pathway prevents cardiac fibrosis

(Medical Xpress)—New research from UC Davis published in the Proceedings of the National Academy of Sciences shows that blocking an enzyme that promotes inflammation can prevent the tissue damage following a heart attack ...

Medical research created Mar 22, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Inactive genes surprisingly common in humans

(Medical Xpress) -- Every person carries on average 100 variants that disable genes - yet very few suffer ill effects, an international team of researchers led by Yale University and Wellcome Trust Sanger ...

Genetics created Feb 16, 2012 | popularity 5 / 5 (4) | comments 1 | with audio podcast

Study uncovers mechanism for how grapes reduce heart failure associated with hypertension

A study appearing in the Journal of Nutritional Biochemistry demonstrates that grapes are able to reduce heart failure associated with chronic high blood pressure (hypertension) by increasing the activity of several genes ...

Cardiology created May 02, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Cystic fibrosis makes airways more acidic, reduces bacterial killing

The human airway is a pretty inhospitable place for microbes. There are numerous immune defense mechanisms poised to kill or remove inhaled bacteria before they can cause problems. But cystic fibrosis (CF) disrupts these ...

Medical research created Jul 04, 2012 | popularity 4.5 / 5 (4) | comments 0 | with audio podcast

Pirfenidone reduces rate of lung decline in idiopathic pulmonary fibrosis

The CAPACITY study, published Online First and in an upcoming Lancet, shows that pirfenidone reduces the rate of decline of lung function in patients with idiopathic pulmonary fibrosis—a condition of unknown cause affect ...

Diseases, Conditions, Syndromes created May 13, 2011 | popularity 5 / 5 (3) | comments 0

Parallel evolution - cystic fibrosis

(Medical Xpress) -- Researchers at the University of Liverpool are examining the evolution of Pseudomonas aeruginosa over time in the lungs of ten people with cystic fibrosis to understand why it persists ...

Medical research created Mar 06, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Study targets key molecule to reverse kidney damage in mice

In findings that may lead to clinical trials of a promising new drug for kidney disease, researchers at Beth Israel Deaconess Medical Center (BIDMC) and their colleagues have identified a key molecular player and shown how ...

Medical research created Mar 07, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers uncover genes at fault for cystic fibrosis-related intestinal obstruction

Researchers at Johns Hopkins have identified a gene that modifies the risk of newborns with cystic fibrosis (CF) developing neonatal intestinal obstruction, a potentially lethal complication of CF. Their findings, which appeared ...

Genetics created Apr 23, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

New proteins to clear the airways in cystic fibrosis and COPD

University of North Carolina scientists have uncovered a new strategy that may one day help people with cystic fibrosis and chronic obstructive pulmonary disorder better clear the thick and sticky mucus that clogs their lungs ...

Diseases, Conditions, Syndromes created Jul 13, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Where chromosomes agree, researchers find signatures of human migrations and marriage practices

(Medical Xpress) -- Your genome is a window onto your heritage – or, more precisely, several windows. There are the marks left by human evolution, the traces of ancient human migrations out of Africa ...

Genetics created Aug 15, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast


Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. This is as opposed to formation of fibrous tissue as a normal constituent of an organ or tissue. Scarring is confluent fibrosis that obliterates the architecture of the underlying organ or tissue.

The term is also sometimes used to describe a normal healing process, but this usage is less common.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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