(Medical Xpress)—A new vaccine against foot-and-mouth disease that is safer to produce and easier to store has been developed by scientists from the University of Oxford and The Pirbright Institute.
Mar 28, 2013
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New research findings may help scientists design drugs to treat a virus infection that causes potentially fatal brain swelling and paralysis in children.
Mar 21, 2013
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(Medical Xpress) -- Skin cells shed from livestock infected with foot and mouth disease could very well spread the disease.
May 10, 2011
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New research shows that in sub-Saharan Africa the virus responsible for foot and mouth disease (FMD) moves over relatively short distances and the African buffalo are important natural reservoirs for the infection. The study, ...
Oct 22, 2013
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The first enterovirus 71 (EV71) vaccine candidate to reach phase 3 clinical testing provides young Chinese children with significant protection against disease caused by EV71, a growing public-health threat which has caused ...
May 28, 2013
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When foot-and-mouth disease swept through the British countryside in early 2001, more than 10 million sheep, cattle and pigs were slaughtered to control the disease. Despite the devastation, the disease was contained within ...
Nov 1, 2012
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(Medical Xpress)—Your child goes to bed in perfect health. The next morning she wakes up with high fever, malaise and bright red blisters erupting all over her body. Johns Hopkins Children's Center dermatologists say the ...
Aug 28, 2012
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(Medical Xpress) -- A mysterious disease that has killed nearly 60 children in Cambodia has been identified by the World Health Organization as enterovirus 71. This virus is one among a family of viruses that causes a variety ...
Jul 11, 2012
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(AP) — A deadly form of a common childhood illness has been linked to the mysterious child deaths in Cambodia that sparked alarm after a cause could not immediately be determined, health officials said Monday.
Jul 9, 2012
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In a worst-case scenario simulation of a foot-and-mouth disease outbreak in Mexico, researchers found that establishing a good surveillance system and raising a more resilient breed of cattle could lessen the blow to the ...
Feb 16, 2012
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Foot-and-mouth disease or hoof-and-mouth disease (Aphtae epizooticae) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever for two or three days, followed by blisters inside the mouth and on the feet that may rupture and cause lameness.
Foot-and-mouth disease is a severe plague for animal farming, since it is highly infectious and can be spread by infected animals through aerosols, through contact with contaminated farming equipment, vehicles, clothing or feed, and by domestic and wild predators. Its containment demands considerable efforts in vaccination, strict monitoring, trade restrictions and quarantines, and occasionally the elimination of millions of animals.
Susceptible animals include cattle, water buffalo, sheep, goats, pigs, antelope, deer, and bison. It has also been known to infect hedgehogs, elephants, llama, and alpaca may develop mild symptoms, but are resistant to the disease and do not pass it on to others of the same species. In laboratory experiments, mice and rats and chickens have been successfully infected by artificial means, but it is not believed that they would contract the disease under natural conditions. Humans are very rarely affected.
The virus responsible for the disease is a picornavirus, the prototypic member of the genus Aphthovirus. Infection occurs when the virus particle is taken into a cell of the host. The cell is then forced to manufacture thousands of copies of the virus, and eventually bursts, releasing the new particles in the blood. The virus is highly variable, which limits the effectiveness of vaccination.
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