Gastroesophageal Reflux Disease

Pill-sized device provides rapid, detailed imaging of esophageal lining

Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine ...

Medical research created Jan 13, 2013 | popularity 4 / 5 (5) | comments 2 | with audio podcast

Study reveals origins of esophageal cancer

(Medical Xpress) -- Researchers at Columbia University Medical Center (CUMC) have identified the critical early cellular and molecular events that give rise to a type of esophageal cancer called esophageal ...

Cancer created Jan 17, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Bile - not acid - is bad guy in triggering precancerous condition associated with reflux disease

For many people with gastroesophageal reflux disease or GERD, acid reflux drugs are the answer to their woes, curbing the chronic heartburn and regurgitation of food or sour liquid characteristic of the disorder. But when ...

Surgery created Apr 24, 2012 | popularity 3 / 5 (2) | comments 0

Genetic link to Barrett's esophagus, esophageal cancer discovered

Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux ...

Genetics created Jul 26, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Pain characteristics suggest higher benefit from gallbladder surgery

According to a new study in Clinical Gastroenterology and Hepatology, better understanding of a patient's abdominal pain could help physicians know which patients will benefit most from surgical removal of the gallbladder. Clinic ...

Other created Oct 12, 2011 | popularity 5 / 5 (1) | comments 0

Risk of esophageal cancer in patients with Barrett’s esophagus

(Medical Xpress) -- A new study published in the New England Journal of Medicine reveals that the risk of patients with Barrett’s esophagus developing adenocarcinoma of the esophagus are not as high as once originally though ...

Cancer created Oct 14, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast report

Study finds physicians show bias when diagnosing stomach problems

Patients who complain of upper gastrointestinal (GI) symptoms often face a diagnosis of either gastroesophageal reflux disease (GERD) or functional dyspepsia. Because the two conditions often overlap, it can be difficult ...

Diseases, Conditions, Syndromes created Oct 31, 2011 | popularity 2.5 / 5 (2) | comments 1

Smoking found to be a risk factor for Barrett's esophagus

(HealthDay) -- Cigarette smoking may be a modifiable risk factor for Barrett's esophagus, according to a study published in the April issue of Gastroenterology.

Diseases, Conditions, Syndromes created Apr 11, 2012 | popularity 5 / 5 (1) | comments 0

Modern treatments for GERD effective at achieving long-term remission for most patients

In an evaluation of contemporary antireflux therapies for chronic gastroesophageal reflux disease (GERD), most patients who received treatment with either the proton pump inhibitor esomeprazole or laparoscopic antireflux ...

Diseases, Conditions, Syndromes created May 17, 2011 | popularity 4 / 5 (1) | comments 0

New research highlights changing epidemiology of Clostridium difficile

A stay in the hospital may not be the only way to acquire Clostridium difficile diarrhea – but the potentially life-threatening infection may be associated with a number of health complications in hospitalized children, accord ...

Diseases, Conditions, Syndromes created Oct 22, 2012 | popularity 2 / 5 (1) | comments 0


Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is a chronic symptom of mucosal damage caused by stomach acid coming up from the stomach into the esophagus. A typical symptom is heartburn.

GERD is usually caused by changes in the barrier between the stomach and the esophagus, including abnormal relaxation of the lower esophageal sphincter, which normally holds the top of the stomach closed; impaired expulsion of gastric reflux from the esophagus, or a hiatal hernia. These changes may be permanent or temporary ("transient").

Another kind of acid reflux, which causes respiratory and laryngeal signs and symptoms, is called laryngopharyngeal reflux (LPR) or "extraesophageal reflux disease" (EERD). Unlike GERD, LPR is unlikely to produce heartburn, and is sometimes called silent reflux.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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