Oncology & Cancer

Enzyme blocker stops growth of deadly brain tumor

Investigators were able to halt the growth of glioblastoma, an aggressive form of brain cancer, by inhibiting an enzyme called CDK5, according to a Northwestern Medicine study published in Cell Reports.

Oncology & Cancer

Insights into how brain cancer evades the immune system

Glioblastoma—a universally fatal form of brain cancer—is known for its ability to hijack immune checkpoints and evade detection and destruction by the body's immune defenses. But many of the details underlying this feat ...

Oncology & Cancer

How CD44s gives brain cancer a survival advantage

Understanding the mechanisms that give cancer cells the ability to survive and grow opens the possibility of developing improved treatments to control or cure the disease. In the case of glioblastoma multiforme, the deadliest ...

Oncology & Cancer

New brain cancer drug targets revealed

Researchers from Case Western Reserve University School of Medicine and The Cleveland Clinic designed a way to screen brain tumor cells and identify potential drug targets missed by other methods. The team successfully used ...

Oncology & Cancer

Scientists find key driver for treatment of deadly brain cancer

Glioblastoma multiforme is a particularly deadly cancer. A person diagnosed with this type of brain tumor typically survives 15 months, if given the best care. The late Senator Ted Kennedy succumbed to this disease in just ...

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