Hay Fever

Sixteen new genetic regions for allergies discovered

(Medical Xpress)—In two of the largest genetic studies ever conducted on common allergies, including pollen, dust-mite and cat allergies, 16 new genetic regions related to the condition have been discovered. ...

Jul 01, 2013
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Three new eczema genes discovered

(Medical Xpress) -- Researchers from Children of the 90s at the University of Bristol, in collaboration with 22 other studies from across the world, have discovered three new genetic variants associated with ...

Dec 26, 2011
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Surviving hay fever

Three million Australian adults – 15% of the population – struggle through spring and summer with watery eyes, running nose, itchy throat and the hallmark hay fever symptom, sneezing. ...

Nov 17, 2014
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11 new genetic associations for asthma-with-hay fever

23andMe has participated in the first ever genome-wide association study of the combined asthma-with-hay fever phenotype. Led by researchers at the QIMR Berghofer Medical Research Institute, the study identified 11 independent ...

Jan 28, 2014
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Common cold meds may pose health threats

(HealthDay)—Over-the-counter sinus and pain remedies that combine two common ingredients—phenylephrine and acetaminophen—might cause serious side effects such as high blood pressure, dizziness and tremors, ...

Mar 19, 2014
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Could 'nasal filter' device help ease allergies?

(HealthDay)— A new device that you wear in your nose—about the size of a contact lens and works like a miniature air filter for a furnace—might help filter out pollen and other allergens and keep them ...

Mar 21, 2014
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Allergic rhinitis is an allergic inflammation of the nasal airways. It occurs when an allergen, such as pollen, dust or animal dander (particles of shed skin and hair) is inhaled by an individual with a sensitized immune system. In such individuals, the allergen triggers the production of the antibody immunoglobulin E (IgE), which binds to mast cells and basophils containing histamine. When caused by pollens of any plants, it is called "pollinosis", and if specifically caused by grass pollens, it is known as "hay fever". Ironically, in hay fever, there is neither any fever nor any hay, but since grasses shed their pollens into the air, at about the same time that hay is being cut, the common term hay fever is used.

IgE bound to mast cells are stimulated by pollen and dust, causing the release of inflammatory mediators such as histamine (and other chemicals). This usually causes sneezing, itchy and watery eyes, swelling and inflammation of the nasal passages, and an increase in mucus production. Symptoms vary in severity between individuals. Very sensitive individuals can experience hives or other rashes. Particulate matter in polluted air, and chemicals such as chlorine and detergents, which can normally be tolerated, can greatly aggravate allergic rhinitis. The physician John Bostock first described hay fever in 1819 as a disease.

Allergies are common. Heredity and environmental exposures may contribute to a predisposition to allergies. It is roughly estimated that one in three people have an active allergy at any given time and at least three in four people develop an allergic reaction at least once in their lives. In Western countries between 10–25% of people annually are affected by allergic rhinitis.

This text uses material from Wikipedia licensed under CC BY-SA

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