Hepatitis B

The therapeutic potential of health data

In the future, doctors won't be concerned about treating just a diseased organ – they'll be using a mass of data to get a holistic view of the state of their patients." This is how the Swiss Centre for Technology Assessment ...

Jun 13, 2016
popularity7 comments 1

Hepatitis B is an infectious inflammatory illness of the liver caused by the hepatitis B virus (HBV) that affects hominoidea, including humans. Originally known as "serum hepatitis", the disease has caused epidemics in parts of Asia and Africa, and it is endemic in China. About a third of the world population has been infected at one point in their lives, including 350 million who are chronic carriers.

The virus is transmitted by exposure to infectious blood or body fluids such as semen and vaginal fluids, while viral DNA has been detected in the saliva, tears, and urine of chronic carriers. Perinatal infection is a major route of infection in endemic (mainly developing) countries. Other risk factors for developing HBV infection include working in a healthcare setting, transfusions, and dialysis, acupuncture, tattooing, extended overseas travel and residence in an institution. However, Hepatitis B viruses cannot be spread by holding hands, sharing eating utensils or drinking glasses, kissing, hugging, coughing, sneezing, or breastfeeding.

The acute illness causes liver inflammation, vomiting, jaundice, and rarely, death. Chronic hepatitis B may eventually cause cirrhosis and liver cancer—a disease with poor response to all but a few current therapies. The infection is preventable by vaccination.

Hepatitis B virus is an hepadnavirus—hepa from hepatotropic (attracted to the liver) and dna because it is a DNA virus—and it has a circular genome of partially double-stranded DNA. The viruses replicate through an RNA intermediate form by reverse transcription, which practice relates them to retroviruses. Although replication takes place in the liver, the virus spreads to the blood where viral proteins and antibodies against them are found in infected people.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Viral protein silences immune alarm signals

Viruses must avoid a host's immune system to establish successful infections—and scientists have discovered another tool that viruses use to frustrate host defenses. Researchers from The Children's Hospital of Philadelphia ...

Rate of decline of cardiovascular deaths slows in US

In a study published online by JAMA Cardiology, Stephen Sidney, M.D., M.P.H., of Kaiser Permanente Northern California, Oakland, and colleagues examined recent national trends in death rates due to all cardiovascular disease ...