Hepatitis C

J&J expects 10-plus new drug applications by 2017

(AP)—Johnson & Johnson is developing what could eventually be game-changing treatments for depression and pain, and it's aiming to apply for approval of more than 10 new medicines by 2017, executives said Thursday during ...

Medications created May 23, 2013 | popularity 5 / 5 (1) | comments 0

Pharmaceutical advances offer new options for health outcomes

Research presented at Digestive Disease Week (DDW) explores pharmaceutical advances for treating irritable bowel syndrome with diarrhea (IBS-D) and hepatitis C.

Diseases, Conditions, Syndromes created May 20, 2013 | popularity not rated yet | comments 0

Twin epidemics: HIV and Hepatitis C in the urban Northeast

A new Yale study looks at the scope and consequences of a burgeoning health problem in the cities of the U.S. Northeast: concurrent infection with both HIV and Hepatitis C (HCV). The study appears online ...

HIV & AIDS created May 17, 2013 | popularity not rated yet | comments 0

Scientists create new tool for identifying powerful HIV antibodies

A team of NIH scientists has developed a new tool to identify broadly neutralizing antibodies (bNAbs) capable of preventing infection by the majority of HIV strains found around the globe, an advance that could help speed ...

HIV & AIDS created May 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

Only half newly reported HCV cases receiving follow-up test

(HealthDay)—The lack of a hepatitis C virus (HCV) RNA test for approximately one-half of persons newly reported as HCV infected suggests that testing and reporting must improve to detect all persons with ...

Diseases, Conditions, Syndromes created May 09, 2013 | popularity not rated yet | comments 0

New antiviral treatment could significantly reduce global burden of hepatitis C

(Medical Xpress)—Around 150 million people globally are chronically infected with the hepatitis C virus (HCV) – a major cause of liver disease and the fastest growing cause of liver transplantation and ...

Diseases, Conditions, Syndromes created May 06, 2013 | popularity not rated yet | comments 0

Hepatitis C screening for baby boomers

If you were born during 1945-1965, talk to your doctor about getting tested for hepatitis C. The word "hepatitis" means swelling of the liver. Hepatitis is most often caused by a virus. In the United States, ...

Diseases, Conditions, Syndromes created Apr 29, 2013 | popularity not rated yet | comments 0

Research finds targeted screening for hepatitis C is cost-effective

Researchers at the University of Cincinnati have found that targeted screening for populations with a higher estimated prevalence for hepatitis C may be cost-effective.

Diseases, Conditions, Syndromes created Apr 24, 2013 | popularity not rated yet | comments 0

Sofosbuvir shows promise for chronic hepatitis C infection

(HealthDay)—Sofosbuvir seems to be a promising treatment option for patients with chronic hepatitis C virus (HCV) infection, according to two studies published online April 23 in the New England Journal of ...

Diseases, Conditions, Syndromes created Apr 23, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Treatment for novel coronavirus shows promise in early lab tests

National Institutes of Health (NIH) scientists studying an emerging coronavirus have found that a combination of two licensed antiviral drugs, ribavirin and interferon-alpha 2b, can stop the virus from replicating ...

Diseases, Conditions, Syndromes created Apr 18, 2013 | popularity not rated yet | comments 0

Potential therapy for HIV suggested: Blocking key protein boosts body's ability to clear chronic infection

UCLA scientists have shown that temporarily blocking a protein critical to immune response actually helps the body clear itself of chronic infection. Published in the April 12 edition of Science, the findin ...

HIV & AIDS created Apr 11, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study finds interferon, one of the body's proteins, induces persistent viral infection

Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C.

Medical research created Apr 11, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Study reveals Rx target for HPV, Hep C and related cancers

New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" ...

Medical research created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Take a kidney transplant now or wait for a better one? Researchers create 'decision' tool

Johns Hopkins scientists have created a free, Web-based tool to help patients decide whether it's best to accept an immediately available, but less-than-ideal deceased donor kidney for transplant, or wait for a healthier ...

Other created Apr 09, 2013 | popularity not rated yet | comments 0

Liver transplantation for patients with genetic liver conditions has high survival rate

Patients faced with the diagnosis of a life-threatening liver disease have to consider the seriousness of having a liver transplant, which can be a definitive cure for many acquired and genetic liver diseases. Among the main ...

Surgery created Apr 05, 2013 | popularity not rated yet | comments 0


Hepatitis C is an infectious disease affecting primarily the liver, caused by the hepatitis C virus (HCV). The infection is often asymptomatic, but chronic infection can lead to scarring of the liver and ultimately to cirrhosis, which is generally apparent after many years. In some cases, those with cirrhosis will go on to develop liver failure, liver cancer or life-threatening esophageal and gastric varices.

HCV is spread primarily by blood-to-blood contact associated with intravenous drug use, poorly sterilized medical equipment and transfusions. An estimated 130–170 million people worldwide are infected with hepatitis C. The existence of hepatitis C (originally "non-A non-B hepatitis") was postulated in the 1970s and proven in 1989. It is not known to cause disease in other animals.

The virus persists in the liver in about 85% of those infected. This persistent infection can be treated with medication; peginterferon and ribavirin are the current standard therapy. Overall, between 50–80% of people treated are cured. Those who develop cirrhosis or liver cancer may require a liver transplant. Hepatitis C is the leading cause of liver transplantation though the virus usually recurs after transplantation. No vaccine against hepatitis C is currently available.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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