Hepatocellular Carcinoma

HIV no barrier to getting liver transplant, study finds

(HealthDay)—Liver transplants to treat a common type of liver cancer are a viable option for people infected with HIV, according to new research.

HIV & AIDS created May 17, 2013 | popularity not rated yet | comments 0

Developments in TACE and SIRT treatment in patients

Data from a number of clinical trials presented today at the International Liver Congress 2013 shed new light on the use of TACE and SIRT in the treatment of hepatocellular carcinoma (HCC).

Cancer created Apr 26, 2013 | popularity not rated yet | comments 0

Cardio could hold key to cancer cure

Regular exercise has been proven to reduce the chance of developing liver cancer in a world-first mice study that carries hope for patients at risk from hepatocellular carcinoma (HCC).

Cancer created Apr 26, 2013 | popularity 5 / 5 (1) | comments 0

Novel screening tests for liver cancer

New data from two clinical trials presented today at the International Liver Congress 2013 demonstrate substantial improvements in the detection of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) using diagnostic ...

Cancer created Apr 26, 2013 | popularity not rated yet | comments 0

Discovery of gene involved in fatty liver disease

An international research consortium led by CIC bioGUNE has discovered the involvement of a gene in the development of non-alcoholic fatty liver disease (NAFLD). Although the gene concerned (SLC2A1) had never previously been ...

Genetics created Apr 24, 2013 | popularity 5 / 5 (1) | comments 0

Liver cancers armed with many strategies for evading immune response

(Medical Xpress)—Researchers at Roswell Park Cancer Institute (RPCI) have published findings that help explain how a common and particularly resilient form of liver cancer evades the body's natural antitumor responses. ...

Cancer created Apr 18, 2013 | popularity not rated yet | comments 0

Engineered small pox may kill liver cancer

As part of a multicenter clinical trial, researchers at University of California, San Diego School of Medicine are evaluating Pexa-Vec (JX-594) to slow the progression of hepatocellular carcinoma (HCC) or liver cancer. Pexa-Vec ...

Cancer created Apr 10, 2013 | popularity 5 / 5 (2) | comments 0

Cancers don't sleep: The Myc oncogene can disrupt circadian rhythm

The Myc oncogene can disrupt the 24-hour internal rhythm in cancer cells. Postdoctoral fellow Brian Altman, PhD, and graduate student Annie Hsieh, MD, both from the in the lab of Chi Van Dang, MD, PhD, director of the Abramson ...

Cancer created Apr 09, 2013 | popularity 3 / 5 (2) | comments 0 | with audio podcast

Better long-term outcomes with low hep C viral load

(HealthDay)—In patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), low HCV viral load predicts better long-term surgical outcomes, regardless of the serologic eradication of HCV, ...

Diseases, Conditions, Syndromes created Mar 25, 2013 | popularity not rated yet | comments 0

Immortality gene mutation identifies brain tumors, other cancers

Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...

Cancer created Mar 18, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Statin use linked to reduced risk of hepatocellular cancer

(HealthDay)—Statin use is associated with a reduced risk of hepatocellular carcinoma (HCC), most strongly in Asian populations, according to a meta-analysis published in the February issue of Gastroenterology.

Cancer created Feb 12, 2013 | popularity not rated yet | comments 0

Teens susceptible to hepatitis B infection despite vaccination as infants

New research reveals that a significant number of adolescents lose their protection from hepatitis B virus (HBV) infection, despite having received a complete vaccination series as infants. Results in the January 2013 issue ...

Diseases, Conditions, Syndromes created Jan 08, 2013 | popularity 5 / 5 (1) | comments 0

Sustained virological response linked with improved survival for patients with chronic HCV infection

Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with ...

Diseases, Conditions, Syndromes created Dec 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Aging hepatitis C population escalates demand for liver transplantation

New research reveals that the greatest demand for liver transplantation due to hepatitis C (HCV)-related liver disease occurs among Americans born between 1941 and 1960. Findings in the December issue of Liver Transplantation, a jour ...

Diseases, Conditions, Syndromes created Dec 06, 2012 | popularity not rated yet | comments 0

NSAID use linked to reduced hepatocellular carcinoma risk and mortality due to chronic liver disease

Researchers found that aspirin use is associated with a decreased risk of developing hepatocellular carcinoma and death from chronic liver disease (CLD), according to a study published November 28 in the Journal of the Na ...

Cancer created Nov 28, 2012 | popularity 4 / 5 (1) | comments 0


Hepatocellular carcinoma (HCC, also called malignant hepatoma) is the most common type of liver cancer. Most cases of HCC are secondary to either a viral hepatitide infection (hepatitis B or C) or cirrhosis (alcoholism being the most common cause of hepatic cirrhosis).

Compared to other cancers, HCC is quite a rare tumor in the United States. In countries where hepatitis is not endemic, most malignant cancers in the liver are not primary HCC but metastasis (spread) of cancer from elsewhere in the body, e.g., the colon. Treatment options of HCC and prognosis are dependent on many factors but especially on tumor size and staging. Tumor grade is also important. High-grade tumors will have a poor prognosis, while low-grade tumors may go unnoticed for many years, as is the case in many other organs, such as the breast, where a ductal carcinoma in situ (or a lobular carcinoma in situ) may be present without any clinical signs and without correlate on routine imaging tests, although in some occasions it may be detected on more specialized imaging studies like MR mammography.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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