Diseases, Conditions, Syndromes

New mechanism in CD47 blockade treatment in HCC

China has the highest morbidity of hepatocellular carcinoma (HCC) in the world. For HCC patients in early stage disease, surgical resection is the best treatment strategy, but most patients in advanced stages lose the opportunity ...

Genetics

Multiomics study of nonalcoholic fatty liver disease

Scientists at deCODE genetics, a subsidiary of Amgen, published today a large genome-wide association study on nonalcoholic fatty liver disease (NAFLD) in Nature Genetics. Sequence variants that associate with NAFLD were ...

Oncology & Cancer

Mailed orders found to double liver cancer screening rates

Liver cancer screening among patients with cirrhosis almost doubled when they were mailed a signed order from their specialist, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. ...

Oncology & Cancer

TB vaccine shrinks liver cancer tumors in mice

A UC Davis Health study found that a single dose of Bacillus Calmette-Guérin (BCG), the vaccine for tuberculosis (TB), reduced liver tumor burden and extended the survival of mice with liver cancer. The study, published ...

Oncology & Cancer

A novel oncogenic network specific to liver cancer initiation

Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, ...

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