Neuroscience

Scientists identify new Huntington disease pathway

(Medical Xpress)—An international group of researchers has identified a major new pathway thought to be involved in the development of Huntington disease. The findings, published in the Proceedings of the National Academy ...

Diseases, Conditions, Syndromes

Uncovering the causes of neuron dysfunction in Huntington's disease

Investigators led by D. James Surmeier, Ph.D., the Nathan Smith Davis Professor and chair of Neuroscience, have uncovered previously unknown neuronal circuits that contribute to brain dysfunction in Huntington's disease.

Neuroscience

Gene therapy in early stages may slow down Huntington's disease

In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage ...

Diseases, Conditions, Syndromes

How Huntington's disease affects different neurons

In patients with Huntington's disease, neurons in a part of the brain called the striatum are among the hardest-hit. Degeneration of these neurons contributes to patients' loss of motor control, which is one of the major ...

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