Hutchinson Gilford Progeria Syndrome

Putting the brakes on accelerated aging

Telomeres are to chromosomes what aglets are to shoelaces—protective caps that stop the tightly wound strings from unraveling. Every time a cell divides, its telomeres are trimmed, eventually becoming so short that the ...

Feb 11, 2016
popularity30 comments 0

Researchers find new clues about aging

National Institutes of Health researchers have identified a new pathway that sets the clock for programmed aging in normal cells. The study provides insights about the interaction between a toxic protein called progerin and ...

Jun 13, 2011
popularity0 comments 0

Aging disease in children sheds light on normal aging

(Medical Xpress) -- Aging of individual cells in the body leads to aging of the whole person. New evidence for this comes from studies of very rare children born with a genetic mutation that wrinkles, ages and kills them ...

Oct 24, 2011
popularity0 comments 0

Progeria (also known as "Hutchinson–Gilford Progeria Syndrome", "Hutchinson–Gilford syndrome", and "Progeria syndrome") is an extremely rare genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. The word progeria comes from the Greek words "pro" (πρό), meaning "before", and "géras" (γῆρας), meaning "old age". The disorder has very low incidences and occurs in an estimated 1 per 8 million live births. Those born with progeria typically live to their mid teens and early twenties. It is a genetic condition that occurs as a new mutation (de novo), and is rarely inherited. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson-Gilford Progeria Syndrome(HGPS).

Scientists are particularly interested in progeria because it might reveal clues about the normal process of aging. Progeria was first described in 1886 by Jonathan Hutchinson. It was also described independently in 1897 by Hastings Gilford. The condition was later named Hutchinson-Gilford Progeria Syndrome (HGPS).

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

High-fat diet starves the brain

A high-fat diet of three days in mice leads to a reduction in the amount of glucose that reaches the brain. This finding was reported by a Research Group led by Jens Brüning, Director at the Max Planck Institute for Metabolism ...

Action recognition without mirror neurons

When someone stands opposite us and purposefully raises their arm to make some kind of movement, our brain asks itself whether they intend to attack us or, perhaps, simply greet us. Scientists from the Department of Human ...

Lifestyle has a strong impact on intestinal bacteria

Everything you eat or drink affects your intestinal bacteria, and is likely to have an impact on your health. That is the finding of a large-scale study led by RUG/UMCG geneticist Cisca Wijmenga into the effect of food and ...