Hutchinson Gilford Progeria Syndrome
Promising treatment for progeria within reach
Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy indicates that the development of progeria ...
Diseases, Conditions, Syndromes
May 16, 2013 |
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Researchers gain insight into abnormally shaped cell nuclei of people with cancer
Misshapen cell nuclei are frequently observed in the cells of people with cancer and other diseases, but what causes the abnormality—and why it is associated with certain disorders—has remained unclear.
Cancer
Feb 19, 2013 |
4.8 / 5 (4) |
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Cellular repair could reduce premature aging
Researchers have identified a potential drug therapy for a premature ageing disease that affects children causing them to age up to eight times as fast as the usual rate.
Genetics
Nov 02, 2011 |
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Study reveals novel mechanism by which UVA contributes to photoaging of skin
A study conducted by researchers at Boston University School of Medicine (BUSM) provides new evidence that longwave ultraviolet light (UVA) induces a protein that could result in premature skin aging. The findings demonstrate ...
Diseases, Conditions, Syndromes
Apr 25, 2013 |
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Possible new drug for children with progeria
(Medical Xpress) -- A new study published in the journal Science Translational Medicine shows that rapamycin and its derivative everolimus, which is currently used to treat cancer and transplant rejections, may wo ...
Diseases, Conditions, Syndromes
Jun 30, 2011 |
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Rapamycin effective in mouse model of inherited heart disease and muscular dystrophies
Rapamycin, an immunosuppressant drug used in a variety of disease indications and under study in aging research labs around the world, improved function and extended survival in mice suffering from a genetic mutation which ...
Medical research
Jul 25, 2012 |
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Progeria: First-ever treatment for rare childhood aging disease shows improvement in all trial participants
Results of the first-ever clinical drug trial for children with Progeria, a rare, fatal "rapid-aging" disease, demonstrate the efficacy of a farnesyltransferase inhibitor (FTI), a drug originally developed to treat cancer. ...
Diseases, Conditions, Syndromes
Sep 24, 2012 |
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Aging disease in children sheds light on normal aging
(Medical Xpress) -- Aging of individual cells in the body leads to aging of the whole person. New evidence for this comes from studies of very rare children born with a genetic mutation that wrinkles, ages and kills them ...
Genetics
Oct 24, 2011 |
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Progeria (also known as "Hutchinson–Gilford Progeria Syndrome", "Hutchinson–Gilford syndrome", and "Progeria syndrome") is an extremely rare genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. The word progeria comes from the Greek words "pro" (πρό), meaning "before", and "géras" (γῆρας), meaning "old age". The disorder has very low incidences and occurs in an estimated 1 per 8 million live births. Those born with progeria typically live to their mid teens and early twenties. It is a genetic condition that occurs as a new mutation (de novo), and is rarely inherited. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson-Gilford Progeria Syndrome(HGPS).
Scientists are particularly interested in progeria because it might reveal clues about the normal process of aging. Progeria was first described in 1886 by Jonathan Hutchinson. It was also described independently in 1897 by Hastings Gilford. The condition was later named Hutchinson-Gilford Progeria Syndrome (HGPS).
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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