A new mechanism that affects how our immune cells perform - and hence their ability to prevent disease - has been discovered by an international team of researchers led by Cambridge scientists.
Aug 1, 2016
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Scientists who analyzed the genes involved in 10 autoimmune diseases that begin in childhood have discovered 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential new targets ...
Aug 24, 2015
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A new paper in Rheumatology finds that rheumatic diseases can lead to reproductive problems, though some conditions have more detrimental effects than others.
Mar 20, 2024
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Arthritis is usually associated with older people, but kids can suffer too. Juvenile idiopathic arthritis (JIA) is the most common type of arthritis in children. It affects about 1 in 1,000 kids under 16 in the UK (roughly ...
Feb 28, 2024
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Doctors might one day be able to target children and young people with arthritis most likely to be helped by its first-line treatment, thanks to the application of machine learning by University of Manchester scientists.
Jan 16, 2024
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Researchers from Skoltech contributed to a large study made by colleagues from Pirogov Russian National Research Medical University, Shemyakin-Ovchinnikov Institute of bioorganic chemistry and other universities and organizations. ...
Nov 27, 2023
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For the first time, scientists have shown that gut bacteria differences are associated with later development of juvenile idiopathic arthritis, a debilitating rheumatic childhood disease, and that these differences are present ...
Jul 6, 2023
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New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, demonstrated that polyarticular juvenile idiopathic arthritis patients were more likely to achieve clinical ...
Nov 8, 2022
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Across Europe, people with rheumatic and musculoskeletal diseases are less able to work than people in the general population. One of the most common reasons is that people with RMDs often have pain caused by their disease. ...
Oct 21, 2022
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Patients with a pediatric onset immune-mediated inflammatory disease (pIMID) have a significantly higher risk of premature death, according to new research being presented today at the 54th Annual Meeting of the European ...
Jun 24, 2022
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Juvenile idiopathic arthritis (JIA) (aka Juvenile Rheumatoid Arthritis JRA) is the most common form of persistent arthritis in children. (Juvenile in this context refers to an onset before age 16, idiopathic refers to a condition with no defined cause, and arthritis is the inflammation of the synovium of a joint.)
JIA is a subset of arthritis seen in childhood, which may be transient and self-limited or chronic. It differs significantly from arthritis commonly seen in adults (osteoarthritis, rheumatoid arthritis), and other types of arthritis that can present in childhood which are chronic conditions (e.g. psoriatic arthritis and ankylosing spondylitis). It is an autoimmune disorder.
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