Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.
Apr 24, 2023
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Children with acute lymphoblastic leukemia (ALL) who live in extreme poverty and were undergoing maintenance therapy faced an almost two-fold greater risk of relapse compared with kids who weren't as poor, according to a ...
Apr 18, 2023
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Tisch Cancer Center scientists have developed unique models of the deadliest blood cancer, acute myeloid leukemia (AML), creating a transformative resource to study this cancer and eventually its drug response and drug resistance. ...
Apr 17, 2023
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Scientists at St. Jude Children's Research Hospital developed a novel combination therapy approach for a leukemia subtype harboring rearrangements in the KMT2A gene. The approach overcomes the cancer's drug resistance, without ...
Apr 11, 2023
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Contrary to previous beliefs, stem cells, from which all new blood cells are formed, remain in bone marrow in the blood cancer type acute lymphocytic leukemia. This disease, however, causes a hidden defect in the stem cells ...
Apr 5, 2023
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Acute myeloid leukemia (AML) is an aggressive blood cancer that causes uncontrolled accumulation of white blood cells. Because of the poor outcomes of this disease, researchers across the globe have been on the hunt for new ...
Apr 4, 2023
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A team of Harvard and Sloan Kettering scientists has developed compounds that can target and degrade proteins associated with acute myeloid leukemia (AML) and nearly doubled the life expectancy of mice with cancer in laboratory ...
Apr 3, 2023
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Cells contain diverse populations of molecules called lipids, which are organic fatty compounds. Lipid metabolism, the synthesis and breakdown of these lipids, plays a key role in regulating the composition and functions ...
Mar 30, 2023
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Why do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop the blood cancer? In a new study published in Blood, scientists from the USC Stem Cell laboratory ...
Mar 23, 2023
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With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug ...
Mar 16, 2023
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