The first gene therapy for cancer, approved by the Food Drug Administration in August, will transform the treatment of a particular kind of cancer in children and young adults. It's transformative because it uses a patient's ...
Oct 2, 2017
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What if a failed leukemia drug could reduce the risk of Alzheimer's disease? A team at the University of Kentucky recently led an effort to investigate this hypothesis. Their results were published today in the journal, Human ...
Apr 3, 2015
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Many children with acute lymphoblastic leukemia (ALL) have a good outcome of their disease. After two years of chemotherapy treatment, 9 out of 10 children are cured. But some children have a more aggressive form of the disease. ...
Dec 10, 2022
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Researchers led by a UCLA bioengineer have developed a therapy—based on two types of cells joined into a single unit—that could help strengthen existing treatments for acute myeloid leukemia. One of the cells is a blood ...
Oct 30, 2018
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Imatinib, better known as Gleevec, was hailed as a "miracle" cancer drug when it entered the market in the early 2000s. Though it has been highly successful at treating early-stage chronic myeloid leukemia (CML)—a rare ...
Jun 1, 2022
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Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS), and increasingly in other diseases, but their mechanism of action is not clear. HMAs may affect many ...
May 26, 2022
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Tyrosine kinases are protein enzymes that have many functions within cells, including cell signaling, growth, and division. Sometimes these enzymes can be overactive, which helps cancer cells survive and multiply. A tyrosine ...
Jul 31, 2020
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Exploration of new leukemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukemia vaccines for clinic use.
Oct 12, 2020
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Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have pinpointed five specific enzymes called protein kinases that play a role when prostate cancer spreads to bone. The discovery ...
Dec 2, 2015
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A new study in JNCI Cancer Spectrum finds that exposure to radiation from CT scans is associated with higher risks of developing thyroid cancer and leukemia.
Nov 19, 2019
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