Like packaging designed to create a protective environment around a product, the mix of cells and fluids immediately surrounding human bone marrow provides critical protective and nourishing conditions for hematopoietic—or ...
Oct 6, 2020
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Researchers have identified a second path to defeating chronic myelogenous leukemia, which tends to affect older adults, even in the face of resistance to existing drugs.
Sep 21, 2020
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Researchers at Children's Hospital of Philadelphia (CHOP) have developed a new computational algorithm that has, for the first time, identified a spectrum of mutations in the noncoding portion of the human genome across five ...
Jul 24, 2020
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A new study by researchers at the RIKEN Center for Integrative Medical Science in Japan reports differences in blood cell mutations between Japanese and European populations. The study found that these pre-clinical mutations ...
Jun 24, 2020
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UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug ...
Jun 18, 2020
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A new study will enable clinicians to identify patients with aggressive leukemia who will not respond to chemotherapy and those who are most likely to benefit from a new immunotherapy.
Jun 5, 2020
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Researchers at Mount Sinai have discovered that human acute myeloid leukemia (AML) stem cells are dependent on a transcription factor known as RUNX1, potentially providing a new therapeutic target to achieve lasting remissions ...
Jun 2, 2020
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Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. A group of researchers led by the University of Zurich have now shown ...
May 8, 2020
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Drug resistance is a major obstacle in cancer treatment—leading to relapse for many patients. In a new study, published online April 20, 2020, in Nature Cell Biology, researchers from the Stowers Institute for Medical Research, ...
Apr 21, 2020
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A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains ...
Apr 20, 2020
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