Leukemia
Researcher investigate 2-drug synergy to treat drug-resistant chronic myeloid leukemia
(Medical Xpress)—An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together ...
Cancer
Oct 24, 2012 |
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Researcher pieces together AML prognosis puzzle
When patients suffering from Acute Myeloid Leukemia (AML) express high levels of the gene, MN1, an already aggressive leukemia is accelerated and shortens survival time. While that's a known fact, the mechanisms involved ...
Cancer
Oct 15, 2012 |
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New tool determines leukemia cells' 'readiness to die,' may guide clinical care
Researchers at Dana-Farber Cancer Institute have developed a novel method for determining how ready acute myeloid leukemia (AML) cells are to die, a discovery that may help cancer specialists to choose treatments option more ...
Cancer
Oct 11, 2012 |
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Deadly complication of stem cell transplants reduced in mice
(Medical Xpress)—Studying leukemia in mice, researchers at Washington University School of Medicine in St. Louis have reduced a life-threatening complication of stem cell transplants, the only curative treatment when leukemia ...
Medical research
Sep 27, 2012 |
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Double assault on tough types of leukemias
Investigators at Northwestern University Feinberg School of Medicine have identified two promising therapies to treat patients with acute megakaryocytic leukemia (AMKL), a rare form of leukemia where the number of cases is ...
Cancer
Sep 20, 2012 |
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Researchers find novel predictor for MDS progression risk
Researchers at Moffitt Cancer Center and colleagues have discovered that changes in the physical characteristics of the effector memory regulatory T cell can predict the progression risk of myelodysplastic syndromes (MDS) ...
Immunology
Sep 13, 2012 |
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New genetic mechanism for controlling blood cell development and blood vessel integrity found
The protein GATA2 is known as a "master regulator" of blood cell development. When a mutation occurs in the gene that makes GATA2, serious blood diseases such as acute myeloid leukemia can result.
Genetics
Sep 10, 2012 |
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Researchers connect new genetic signature to leukemia
(Medical Xpress)—University of Rochester Medical Center scientists believe they are the first to identify genes that underlie the growth of primitive leukemia stem cell, and then to use the new genetic signature to identify ...
Cancer
Aug 27, 2012 |
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Gene discovery could improve treatment for acute myeloid leukemia
Scientists at Albert Einstein College of Medicine of Yeshiva University have made a discovery involving mice and humans that could mean that people with acute myeloid leukemia (AML), a rare and usually fatal cancer, are a ...
Cancer
Aug 13, 2012 |
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Existing drugs offer new treatment options for high-risk childhood leukemia subtype
Scientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.
Cancer
Aug 13, 2012 |
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Tumor cells' inner workings predict cancer progression
Using a new assay method to study tumor cells, researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center have found evidence of clonal evolution in chronic ...
Cancer
Jul 27, 2012 |
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Hundreds of random mutations in leukemia linked to aging, not cancer
Hundreds of mutations exist in leukemia cells at the time of diagnosis, but nearly all occur randomly as a part of normal aging and are not related to cancer, new research shows.
Genetics
Jul 19, 2012 |
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miR loss may power maligant transformation in chronic leukemia
Loss of a particular microRNA in chronic lymphocytic leukemia shuts down normal cell metabolism and turns up alternative mechanisms that enable cancer cells to produce the energy and build the molecules they need to proliferate ...
Cancer
Jul 05, 2012 |
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Researchers discover rare leukemia-causing protein
Researchers at the University of Cincinnati (UC) Hoxworth Blood Center have discovered a new gene target for leukemia therapy.
Cancer
Jul 02, 2012 |
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Inhibitors of shuttle molecule show promise in acute leukemia
A novel family of experimental agents that blocks a molecule from shuttling proteins out of the cell nucleus might offer a new treatment for people with acute leukemia, according to a study by researchers at the Ohio State ...
Cancer
Jun 19, 2012 |
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Leukemia (American English) or leukaemia (British English) (from the Greek leukos λεύκος - white, and haima αίμα - blood) is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases affecting the blood, bone marrow, heart, and lymphoid system, which are all known as hematological neoplasms. Leukemia can also cause multiple organ failure.
In 2000, approximately 256,000 children and adults around the world developed some form of leukemia, and 209,000 died from it.[citation needed]
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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