Genetics

New clues to treat Alagille syndrome from zebrafish

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies potential new therapeutic avenues for patients with Alagille syndrome. The discovery, published in Nature Communications, ...

Diseases, Conditions, Syndromes

Plant toxin causes biliary atresia in animal model

A study in this week's Science Translational Medicine is a classic example of how seemingly unlikely collaborators can come together to make surprising discoveries. An international team of gastroenterologists, pediatricians, ...

Medical research

Stopping liver failure from painkiller overdose

(Medical Xpress)—University of Adelaide researchers have identified a key step for the future prevention of liver failure resulting from taking too much of the everyday painkiller paracetamol (also known as acetaminophen).

Neuroscience

Drug shows early promise in treating seizures

A study out today in the journal Nature Medicine suggests a potential new treatment for the seizures that often plague children with genetic metabolic disorders and individuals undergoing liver failure. The discovery hinges ...

Medical research

Liver fat gets a wake-up call that maintains blood sugar levels

A Penn research team, led by Mitchell Lazar, MD, PhD, director of the Institute for Diabetes, Obesity, and Metabolism at the Perelman School of Medicine, University of Pennsylvania, reports in Nature Medicine that mice in ...

Medical research

Researchers find novel way to prevent drug-induced liver injury

Massachusetts General Hospital (MGH) investigators have developed a novel strategy to protect the liver from drug-induced injury and improve associated drug safety. In their report receiving advance online publication in ...

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